Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | disease | BEFREE | This study postulates that this reflects a common genetic cause, and investigates whether the INSR rs2059806 single nucleotide polymorphism (SNP) (a risk factor for essential hypertension, type 2 diabetes and metabolic syndrome) is also associated with pre-eclampsia. | 28117222 | 2017 | ||||
|
0.070 | Biomarker | disease | BEFREE | Insulin receptor number is reduced in healthy offspring of patients with essential hypertension. | 15485753 | 2004 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The first molecular genetic association with human essential hypertension (HT) involved the insulin receptor gene (INSR). | 9247738 | 1997 | ||||
|
0.070 | Biomarker | disease | BEFREE | Thus, the results from this study do not support a role for the INSR gene in the genesis of essential hypertension in the population studied. | 8523386 | 1995 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The present study examined genotypes for the obesity-associated ApaLI restriction fragment length polymorphism of LDLR, and genotypes for a hypertension-associated RsaI restriction fragment length polymorphism at the insulin receptor gene (INSR) locus, which is linked to LDLR, in relation to plasma lipids, body mass index and blood pressure in 27 obese and 57 non-obese Caucasians with severe essential hypertension, selected on the basis of having parents who were both hypertensive, and in 25 obese and 45 non-obese normotensive subjects selected on the basis of having parents who were both normotensive after the age of 50 years.2. | 7913431 | 1994 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Short report: insertion variant in intron 9, but not microsatellite in intron 2, of the insulin receptor gene is associated with essential hypertension. | 8301111 | 1993 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Independent, marked associations of alleles of the insulin receptor and dipeptidyl carboxypeptidase-I genes with essential hypertension. | 8104754 | 1993 |