Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.100 GeneticVariation phenotype BEFREE Anxiety and depression symptom scores from the SCL-90 questionnaire were observed in a large sample of nuclear families, and the effects of genes or family environment were estimated. 1827639 1991
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.100 GeneticVariation phenotype BEFREE Anxiety and depression symptom scores from the SCL-90 questionnaire were observed in a large sample of nuclear families, and the effects of genes or family environment were estimated. 1827639 1991
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.100 GeneticVariation phenotype BEFREE Anxiety and depression symptom scores from the SCL-90 questionnaire were observed in a large sample of nuclear families, and the effects of genes or family environment were estimated. 1827639 1991
Entrez Id: 100379198
Gene Symbol: ECT
ECT
0.040 Biomarker phenotype BEFREE The frequency of depressive symptoms in anorexic patients, the response of some anorexic patients to antidepressants or ECT, the occurrence of comparable physiologic abnormalities in major depression and anorexia nervosa, and family studies of incidence increasingly link depression and anorexia in the literature. 3882007 1985
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.330 Biomarker phenotype BEFREE Associations between self-reported depressive symptoms and exposure to angiotensin converting enzyme inhibitors or calcium channel blockers were not observed. 7553546 1995
Entrez Id: 3352
Gene Symbol: HTR1D
HTR1D
0.010 Biomarker phenotype BEFREE We report on 5-HT1A, 5-HT1D, and 5-HT2 binding sites in 23 control subjects and 18 suicide victims subdivided according to the method of death and the previous existence of depressive symptoms. 8018797 1994
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.030 GeneticVariation phenotype BEFREE At follow-up, noncarriers of BRCA1 mutations showed statistically significant reductions in depressive symptoms and functional impairment compared with carriers and nontested individuals. 8648868 1996
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.100 Biomarker phenotype BEFREE These findings explain, for example, the efficacy of estrogen therapy or 5-HT uptake blockers such as fluoxetine in treating the depressive symptoms of the premenstrual syndrome. and suggest that the sex differences in schizophrenia may also be due to an action of estrogen mediated by way of 5-HT2A receptors.3. 8818400 1996
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.030 GeneticVariation phenotype BEFREE After a baseline assessment of demographics, objective risk, cancer-specific distress, and global distress (depressive symptoms), study participants were offered the opportunity to receive genetic counseling and to learn whether they carry a mutation in the BRCA1 gene. 9170764 1997
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 GeneticVariation phenotype BEFREE These results do not support an association between depressive symptoms and Apo E allele status in this elderly African-American population. 9363291 1997
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.030 GeneticVariation phenotype BEFREE The intent of this study was to evaluate the effect that an awareness of being a BRCA1 or BRCA2 mutation carrier has on the attitude towards prophylactic surgery and on developing depression symptoms. 10755396 2000
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.010 GeneticVariation phenotype BEFREE The intent of this study was to evaluate the effect that an awareness of being a BRCA1 or BRCA2 mutation carrier has on the attitude towards prophylactic surgery and on developing depression symptoms. 10755396 2000
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 GeneticVariation phenotype BEFREE No association was observed between APOE genotype and change in depressive symptoms. 10910416 2000
Entrez Id: 3630
Gene Symbol: INS
INS
0.010 Biomarker phenotype BEFREE The HUMTH01 and INS-VNTR were associated with insulin resistance and depressive symptoms. 11016895 2000
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 GeneticVariation phenotype BEFREE The relationship between deep WMHs and depressive symptoms was especially strong in individuals carrying the APOE-4 allele. 11384894 2001
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.030 Biomarker phenotype BEFREE We have shown that treatment with interleukin-2 (IL-2) or interferon-alpha (IFN alpha) may induce depressive symptoms and activation of the cytokine network and that IL-2 treatment may diminish serum dipeptidyl pepdidase IV (DPP IV) activity. 11443537 2001
Entrez Id: 367
Gene Symbol: AR
AR
0.050 GeneticVariation phenotype BEFREE Testosterone level, androgen receptor polymorphism, and depressive symptoms in middle-aged men. 11543741 2001
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.100 GeneticVariation phenotype BEFREE This study investigated the relationship between depressive symptom response during tryptophan (TRP) depletion and a functional polymorphism of the promoter region of the serotonin (5-HT) transporter gene (SLC6A4).(1) Forty-three subjects in remission from a major depressive episode who underwent TRP depletion were genotyped. 11840315 2002
Entrez Id: 9968
Gene Symbol: MED12
MED12
0.010 GeneticVariation phenotype BEFREE HOPA variant subjects continued to show significant differences in depressive symptoms when controlling for gene-environment interaction. 12216017 2002
Entrez Id: 1055
Gene Symbol: CECR
CECR
0.100 GeneticVariation phenotype BEFREE In bivariate analyses, non-shared environmental factors accounted for the majority of covariation between liability to depressive symptoms (CES-D scores > or = 8; above the 75th percentile) and liability to current and lifetime smoking status. 12745509 2003
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.100 GeneticVariation phenotype BEFREE 5-HTTLPR variants had no influence on reduction of depressive symptoms on day 2 or relapse on day 3. 12872203 2003
Entrez Id: 348
Gene Symbol: APOE
APOE
0.100 GeneticVariation phenotype BEFREE The APOE-epsilon4 allele (but not baseline mild depressive symptoms) is associated with verbal memory decline in middle-aged and older persons. 14609807 2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.100 Biomarker phenotype BEFREE Interleukin-1beta (IL-1beta) gene and increased risk for the depressive symptom-dimension in schizophrenia spectrum disorders. 14681906 2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.100 GeneticVariation phenotype BEFREE Association between interleukin 1-beta promoter (-511) polymorphism and depressive symptoms in Alzheimer's disease. 14681913 2004
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
0.010 GeneticVariation phenotype BEFREE To study depressive symptoms in preclinical presenilin-1 (PS1) related Alzheimer's disease. 14966176 2004