Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | Biomarker | disease | BEFREE | This study found no statistically significant association between CEL-HYB1 and chronic pancreatitis in a cohort of Polish pediatric CP patients. | 31036489 | 2019 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | This allele (CEL-HYB) encodes a chimeric protein with impaired secretion increasing five-fold the risk for chronic pancreatitis. | 29233499 | 2018 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | A hybrid allele between the carboxyl ester lipase gene (CEL) and its pseudogene, CELP (called CEL-HYB), generated by nonallelic homologous recombination between CEL intron 10 and CELP intron 10', was found to increase susceptibility to chronic pancreatitis in a case-control study of patients of European ancestry. | 26946345 | 2016 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | We tested the hypothesis that a deletion and frameshift mutation (C563fsX673) in the CEL VNTR causes CP through proteotoxic gain-of-function activation of maladaptive cell signaling pathways including cell death pathways. | 27650499 | 2016 | ||||
|
0.370 | Biomarker | disease | BEFREE | Here, we aimed to investigate a potential association of CEL VNTR lengths with alcoholic CP. | 27802312 | 2016 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. | 25774637 | 2015 | ||||
|
0.370 | Biomarker | disease | CTD_human | A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. | 25774637 | 2015 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | This study did not find evidence that supported an association between the common length variations of the CEL VNTR and chronic pancreatitis. | 23395566 | 2013 |