| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | AlteredExpression | disease | BEFREE | Inhibition of ATF6 or p53 suppressed the expression of inflammatory factors and progression of CP in the mouse model. | 31506423 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer. | 17659731 | 2007 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | We analyzed ppENK hypermethylation in pure pancreatic juice (PPJ) in patients with PCa, intraductal papillary mucinous neoplasms (IPMN), and chronic pancreatitis (CP), and elucidated its usefulness as a marker in the diagnosis of PCa compared with p53 mutation. | 16988769 | 2006 | ||||
|
0.090 | Biomarker | disease | BEFREE | Relationship between K-ras mutation and the expression of p21WAF1/CIP1 and p53 in chronic pancreatitis and pancreatic adenocarcinoma. | 14628083 | 2003 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | It was the aim of this study to evaluate the presence and clinical significance of p53 and ras mutations in clinical pancreatic juice samples from patients with chronic pancreatitis. | 11375580 | 2001 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Ductal lesions in patients with CP exhibit K-ras mutations without additional indications of neoplastic transformation such as severe dysplasia or mutated p53 protein. | 10861425 | 2000 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Genetic alterations in chronic pancreatitis: evidence for early occurrence of p53 but not K-ras mutations. | 9529487 | 1998 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | These data support a role for p53 gene alterations in human pancreatic cancer, and suggest that loss of its regulatory functions may constitute one of the differences between pancreatic cancer and chronic pancreatitis. | 8513440 | 1993 | ||||
|
0.090 | Biomarker | disease | BEFREE | Nuclear immunoreactivity to the p53 protein in pancreatic biopsy is more suggestive of a malignant tumour than chronic pancreatitis. | 8218996 | 1993 |