Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 60
Gene Symbol: ACTB
ACTB
0.010 AlteredExpression group BEFREE From two independent proteomic analyses using circulating EVs from ME/CFS, healthy controls, idiopathic chronic fatigue, and depression, proteins identified from ME/CFS patients are involved in focal adhesion, actin skeletal regulation, PI3K-Akt signaling pathway, and Epstein-Barr virus infection. 31759091 2020
Entrez Id: 4521
Gene Symbol: NUDT1
NUDT1
0.010 AlteredExpression group BEFREE MTH1, OGG1, and MUTYH were upregulated upon EBV infection in primary B-cells and treatment with MTH1 inhibitors prevented B-cell immortalization. 31511648 2020
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3
0.010 Biomarker group BEFREE FOXO3 protein is repressed by EBV infection. 31712122 2020
Entrez Id: 1847
Gene Symbol: DUSP5
DUSP5
0.010 AlteredExpression group BEFREE In this study, we found that DUSPs generally are down-regulated post EBV infection. 31776277 2020
Entrez Id: 4968
Gene Symbol: OGG1
OGG1
0.010 AlteredExpression group BEFREE MTH1, OGG1, and MUTYH were upregulated upon EBV infection in primary B-cells and treatment with MTH1 inhibitors prevented B-cell immortalization. 31511648 2020
Entrez Id: 969
Gene Symbol: CD69
CD69
0.010 AlteredExpression group BEFREE The aim of the present study was to analyze early and late activation of T-lymphocytes related to Epstein-Barr virus (EBV) infection by the expression of markers of activation (CD69, CD25) on the surface of T-lymphocytes (CD3<sup>+</sup>, CD4<sup>+</sup>, CD8<sup>+</sup>) in patients bearing laryngeal cancer according to absence/presence immunoglobulin G antibodies to EBV nuclear antigen (EBNA1). 31662531 2020
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.010 Biomarker group BEFREE Epstein-Barr virus infection status and mismatch repair (MMR) enzyme-silencing/p53/mucin expression were examined by in situ hybridization and immunohistochemistry, respectively. 30625481 2019
Entrez Id: 6046
Gene Symbol: BRD2
BRD2
0.010 Biomarker group BEFREE These included genes postulated to be involved in magnesium transport (NIPAL1), EBV cell entry (ITGB6), modulation of EBV infection (BCL2L12, NEDD4L), telomere biology (CLPTM1L, BRD2, HNRNPU), modulation of cAMP signaling (RAPGEF3), DNA repair (PRKDC, MLH1), and Notch signaling (NOTCH1, DLL3). 31289279 2019
Entrez Id: 3604
Gene Symbol: TNFRSF9
TNFRSF9
0.010 Biomarker group BEFREE This novel immunodeficiency demonstrates the critical role of 4-1BB costimulation in host immunity against EBV infection. 30872117 2019
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
0.010 Biomarker group BEFREE If peripheral T cell lymphoma or T cell lymphomas of follicular helper origin are considered in the differential diagnosis, the following panel is recommended: pan T cell antigens, CD4, CD8, one or more follicular dendritic cell markers, and assessment for Epstein-Barr virus (EBV) infection, preferably EBV encoded RNA (EBER) as assessed by in situ hybridization When the differential diagnosis includes nodular lymphocyte predominant Hodgkin lymphoma, recommended additional studies include OCT2, CD21 and/or CD23, PD1, and assessment for EBV infection. 30802809 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
0.010 Biomarker group BEFREE Here, we investigated EBV infection-induced Nrf2 activation in B cells by analyzing translocation of Nrf2 from the cytosol to the nucleus. 30909091 2019
Entrez Id: 56998
Gene Symbol: CTNNBIP1
CTNNBIP1
0.010 AlteredExpression group BEFREE In the absence of EBV infection, lower expression of CTNNBIP1 was observed. 30076728 2019
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
0.010 Biomarker group BEFREE These included genes postulated to be involved in magnesium transport (NIPAL1), EBV cell entry (ITGB6), modulation of EBV infection (BCL2L12, NEDD4L), telomere biology (CLPTM1L, BRD2, HNRNPU), modulation of cAMP signaling (RAPGEF3), DNA repair (PRKDC, MLH1), and Notch signaling (NOTCH1, DLL3). 31289279 2019
Entrez Id: 23164
Gene Symbol: MPRIP
MPRIP
0.010 Biomarker group BEFREE This study aims to explore the epigenetic mechanisms allowing cancer cells with EBV infection to escape from RIP3-dependent necroptosis. 31131045 2019
Entrez Id: 1130
Gene Symbol: LYST
LYST
0.010 GeneticVariation group BEFREE This is the first case report in which adult HLH was associated with novel digenic mutations of STXBP2 and LYST combined with Epstein-Barr virus infection. 30782130 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.010 AlteredExpression group BEFREE IL-17A was statistically associated with tissue differentiation, serum EBV-lgA levels, and EBV infection. 31456038 2019
Entrez Id: 10219
Gene Symbol: KLRG1
KLRG1
0.010 Biomarker group BEFREE Finally, PD-1+, Tim-3+, and KLRG1+ CD8+ T cell expansion coincided with declining viral loads during low dose EBV infection. 31145756 2019
Entrez Id: 3070
Gene Symbol: HELLS
HELLS
0.010 Biomarker group BEFREE The levels of Ki67, LSH, 5-hmC, and E2F1 were all increased in germinal center B-cell lymphomas when compared with those in normal lymph nodes, and LSH was highly expressed in diffuse large B-cell lymphomas (DLBCLs) and Burkitt lymphomas (BLs) that were positive for Epstein-Barr virus (EBV) infection, indicating that LSH is linked to EBV infection in DLBCL and BL. 30964110 2019
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
0.010 Biomarker group BEFREE Host cell transcriptional changes in response to EBV infection classified tumors into two molecular subtypes based on patterns of IFN signature genes and immune checkpoint markers, such as PD-L1 and IDO1. 31481499 2019
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
0.010 Biomarker group BEFREE Since methylation can affect gene expression, and so cell differentiation and immune evasion, we hypothesised that EBV-driven hypomethylation may affect the interaction between EBV infection and MS. We interrogated an existing dataset comprising three individuals with whole-genome bisulfite sequencing data from EBV transformed B cells and CD40L-activated B cells. 31619767 2019
Entrez Id: 10666
Gene Symbol: CD226
CD226
0.010 Biomarker group BEFREE We found that CD226 expression on B cells was independent of B-cell activation as CpG DNA failed to induce CD226 to the extent of EBV infection. 29202043 2019
Entrez Id: 84678
Gene Symbol: KDM2B
KDM2B
0.010 Biomarker group BEFREE Interplay between the Epigenetic Enzyme Lysine (K)-Specific Demethylase 2B and Epstein-Barr Virus Infection. 30996097 2019
Entrez Id: 10683
Gene Symbol: DLL3
DLL3
0.010 GeneticVariation group BEFREE These included genes postulated to be involved in magnesium transport (NIPAL1), EBV cell entry (ITGB6), modulation of EBV infection (BCL2L12, NEDD4L), telomere biology (CLPTM1L, BRD2, HNRNPU), modulation of cAMP signaling (RAPGEF3), DNA repair (PRKDC, MLH1), and Notch signaling (NOTCH1, DLL3). 31289279 2019
Entrez Id: 152519
Gene Symbol: NIPAL1
NIPAL1
0.010 Biomarker group BEFREE These included genes postulated to be involved in magnesium transport (NIPAL1), EBV cell entry (ITGB6), modulation of EBV infection (BCL2L12, NEDD4L), telomere biology (CLPTM1L, BRD2, HNRNPU), modulation of cAMP signaling (RAPGEF3), DNA repair (PRKDC, MLH1), and Notch signaling (NOTCH1, DLL3). 31289279 2019
Entrez Id: 2239
Gene Symbol: GPC4
GPC4
0.010 GeneticVariation group BEFREE The distribution of GPC4 polymorphism rs1048369 was investigated in NPC patients, especially in those with EBV infection. 31522169 2019