Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 AlteredExpression group BEFREE Recent evidence has shown that the Epstein-Barr virus (EBV) oncogene LMP1 is not expressed at high levels early after EBV infection of primary B cells, despite its being essential for the long-term outgrowth of immortalized lymphoblastoid cell lines (LCLs). 29118124 2018
Entrez Id: 10718
Gene Symbol: NRG3
NRG3
0.100 GeneticVariation group GWASCAT Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples. 28654678 2017
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
0.100 GeneticVariation group GWASCAT Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples. 28654678 2017
Entrez Id: 7273
Gene Symbol: TTN
TTN
0.100 GeneticVariation group GWASCAT Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples. 28654678 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 AlteredExpression group BEFREE We conclude that in RA patients with MTX-BLPD, EBV infection is associated with a lower incidence of CIMP, apoptosis-related gene hypermethylation, and BCL2 expression, which can induce tumor regression by MTX withdrawal and lead to better prognoses. 27864689 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 Biomarker group BEFREE Although Epstein-Barr virus (EBV) infection and MYC translocations are hallmarks of the disease, it is unclear whether other factors may contribute to its development. 26468873 2016
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 AlteredExpression group BEFREE Here we show that Epstein Barr virus (EBV) infection of primary human B-cells leads to the down-regulation of DOK1 gene expression via the viral oncoprotein LMP1. 24809689 2015
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 GeneticVariation group BEFREE We therefore investigated the incidence of latent EBV infection in a group of patients with leukemic low-grade B-NHL, as well as the incidence of viral latent membrane protein 1 (LMP1) oncoprotein expression in the same patient group. 24261679 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation group BEFREE We found that resistance to spindle poison-induced apoptosis could be reverted in tumor protein p53 (TP53)-mutated cells by EBV (Epstein Barr virus) infection. 24787013 2015
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
0.100 AlteredExpression group BEFREE The unique bimodal intracellular SAP protein expression indicated the presence of some residual SAP-positive T cells that are able to respond to persistent Epstein-Barr virus infection and could explain the relatively mild clinical phenotype of this patient. 25044636 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 GeneticVariation group BEFREE Here, we report a rare case of gastrointestinal (GI)-ARL with MYC rearrangements and coinfected with Epstein-Barr virus (EBV) infection presenting with various endoscopic findings. 23922484 2014
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 AlteredExpression group BEFREE The activation of MYC oncogene in these lymphomas may be an important pathogenetic element associated with Epstein-Barr virus infection. 22899491 2014
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 AlteredExpression group BEFREE Our aim was to correlate Fc-γ RIIA polymorphisms, by studying the prevalence of each allele using PCR-RFLPs (polymerase chain reaction-restriction fragment length polymorphisms), with latent Epstein-Barr virus (EBV) infection and the expression of latent membrane protein 1 (LMP1) in 40 patients with leukemic low grade B-cell lymphomas. 23270585 2014
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 Biomarker group BEFREE Elucidation of the mechanisms involved in LMP1-induced genomic instability in nasopharyngeal epithelial cells will shed lights on the understanding of role of EBV infection in NPC development. 22761726 2013
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 GeneticVariation group BEFREE These transformed tumors are clinically, histologically, and phenotypically similar to primary plasmablastic lymphomas, but they are not associated with immunodeficiency and rarely have Epstein-Barr virus infection or MYC alterations. 23282972 2013
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
0.100 GeneticVariation group GWASCAT A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). 23326239 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 AlteredExpression group BEFREE We detected p63 and p53 expression using immunohistochemistry staining in 84 cases of NKTCL from Southern of China, an area with a well known high incidence of nasopharyngeal carcinoma, which is closely associated with Epstein-Barr virus infection. 23626008 2013
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
0.100 GeneticVariation group BEFREE Patients with the primary immunodeficiency X-linked lymphoproliferative disease (XLP), which is caused by mutations in SH2D1A, are highly susceptible to Epstein-Barr virus (EBV) infection. 22493517 2012
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 Biomarker group BEFREE Thus, antibodies induced against LMP1 during Epstein-Barr virus infection might act as inflammatory trigger by reacting with MBP, suggesting molecular mimicry in the mechanism of MS pathogenesis. 21859892 2012
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 AlteredExpression group BEFREE However, despite documentation of EBV infection by expression of EBNA2 and LMP1, B-CLL cells died after removal of macrophage feeder cells. 22160618 2012
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 Biomarker group BEFREE EBV infection was localized by EBV-encoded RNA (EBER) in situ hybridization and by immunohistochemical stains for viral latent proteins LMP1 and LMP2 and for viral lytic proteins BMRF1 and BZLF1. 22410851 2012
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
0.100 Biomarker group BEFREE Although previous studies have identified defects in lymphocytes from XLP patients, the unique role of SAP in controlling EBV infection remains unresolved. 22069374 2012
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
0.100 Biomarker group BEFREE The signaling lymphocyte activation molecule (SLAM)-associated protein, SAP, was first identified as the protein affected in most cases of X-linked lymphoproliferative (XLP) syndrome, a rare genetic disorder characterized by abnormal responses to Epstein-Barr virus infection, lymphoproliferative syndromes, and dysgammaglobulinemia. 21219180 2011
Entrez Id: 9260
Gene Symbol: PDLIM7
PDLIM7
0.100 AlteredExpression group BEFREE We show that BLIMP1α expression is down-regulated after EBV infection of primary germinal center B cells and that the EBV oncogene, latent membrane protein-1 (LMP-1), is alone capable of inducing this down-regulation in these cells. 21411757 2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.100 Biomarker group BEFREE Our results reinforce the notion that EBV infection and MYC rearrangements are important events in the pathogenesis of oral PBL. 21783402 2011