Gene: SIRT1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.220 AlteredExpression disease BEFREE Multivariate logistic regression analysis revealed higher serum SIRT1 level independently predicted LVH in hypertensive patients (OR 1.50; 95% CI, 1.30-1.73; <i>P</i> < 0.001). 30230925 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.220 Biomarker disease BEFREE Pressure overload-induced left ventricular (LV) hypertrophy was attenuated in mice with heterozygous knockout of either PPARα (PPARα (+/-) ) or Sirt1 (Sirt1 (+/-) ), whereas cardiac-specific PPARα and Sirt1 bigenic mice showed LV hypertrophy accompanied by a high mortality rate even without pressure overload. 22333581 2012
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.220 Biomarker disease RGD Hypertensive left ventricular hypertrophy was significantly and positively related to the expression of heart tissue sirt1 mRNA in SHR. 19142216 2009
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.220 Biomarker disease RGD Forkhead class O transcription factor 3a activation and Sirtuin1 overexpression in the hypertrophied myocardium of the diabetic Goto-Kakizaki rat. 18192848 2008