Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.310 AlteredExpression disease BEFREE Endothelin-1 is upregulated in oral mucosal inflammation, although it has not been shown to induce pain in oral ulcers. 29518348 2018
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.310 Therapeutic disease CTD_human Role of endothelin-1-dependent up-regulation of leptin in oral mucosal repair. 16391412 2005
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Therapeutic disease CTD_human Role of endothelin-1-dependent up-regulation of leptin in oral mucosal repair. 16391412 2005
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.120 Biomarker disease BEFREE Other significant findings include the association between risk alleles in FCGR2A and malar rash (p=0.0031, OR 1.11, 95% CI 1.17 to 1.33), ITGAM and discoid rash (p=0.0020, OR 1.20, 95% CI 1.06 to 1.33), STAT4 and protection from oral ulcers (p=0.0027, OR 0.89, 95% CI 0.83 to 0.96) and IL21 and haematological disorder (p=0.0027, OR 1.13, 95% CI 1.04 to 1.22). 21719445 2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.120 Biomarker disease BEFREE In contrast, STAT4 was less strongly associated with oral ulcers, a manifestation associated with milder disease. 18516230 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.120 Biomarker disease HPO
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.110 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 6891
Gene Symbol: TAP2
TAP2 		0.110 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.110 GeneticVariation disease BEFREE In addition, the combined frequencies of IL-10 A/T/A haplotype and TNF-alpha G-G genotype were significantly decreased in patients with oral ulcers. 20576226 2010
Entrez Id: 6891
Gene Symbol: TAP2
TAP2 		0.110 GeneticVariation disease BEFREE The allele frequency of TAP2*Bky2 was significantly higher in SLE patients with oral ulcers than in those without. 12729048 2003
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.110 Biomarker disease HPO
Entrez Id: 1589
Gene Symbol: CYP21A2
CYP21A2 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 105377068
Gene Symbol: LINC02009
LINC02009 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 79792
Gene Symbol: GSDMD
GSDMD 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 6239
Gene Symbol: RREB1
RREB1 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 3594
Gene Symbol: IL12RB1
IL12RB1 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 100130988
Gene Symbol: SPATA48
SPATA48 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 170680
Gene Symbol: PSORS1C2
PSORS1C2 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 5536
Gene Symbol: PPP5C
PPP5C 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 101928376
Gene Symbol: IL12A-AS1
IL12A-AS1 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 50604
Gene Symbol: IL20
IL20 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
Entrez Id: 10919
Gene Symbol: EHMT2
EHMT2 		0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019