Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 29126
Gene Symbol: CD274
CD274
0.010 Biomarker group BEFREE However, the role of PD-L1/PD-1 in migraine remains unclear. 31640402 2020
Entrez Id: 633
Gene Symbol: BGN
BGN
0.010 Biomarker group BEFREE The Migraine Disability Assessment (MIDAS), Patient Global Impression of Severity (PGI-S), Patient Global Impression of Improvement (PGI-I), and migraine headache days (MHD) served as anchors. 30861580 2019
Entrez Id: 412
Gene Symbol: STS
STS
0.010 GeneticVariation group BEFREE Kinesiophobia and clinical migraine features were not significantly associated (P > 0.05), nor were TSK score, ASC-12 score, or clinical migraine features (r < 0.21, P > 0.05). 30462312 2019
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
0.010 Biomarker group BEFREE Although non-specific, serum NLR, MLR, PLR, and CAR levels may be potential biomarkers associated with migraine subtypes with different clinical features such as migraine attack period, migraine with aura, and patients with family history of migraine. 31758522 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.010 Biomarker group BEFREE Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model. 30971286 2019
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
0.010 Biomarker group BEFREE In this study, therefore, we investigated anti-nociceptive effects of WIN 55,212-2, and the role of either CB<sub>1</sub> or CB<sub>2</sub> receptors in nitroglycerine (NTG)-induced animal model of migraine. 31330139 2019
Entrez Id: 9622
Gene Symbol: KLK4
KLK4
0.010 Biomarker group BEFREE Arm 1 comprised 33 216 patients with FM and arm 2 consisted of 7420 patients with migraine; all of these patients were diagnosed between 2000 and 2010. 30962236 2019
Entrez Id: 7454
Gene Symbol: WAS
WAS
0.010 GeneticVariation group BEFREE We sought to determine whether inhalation of cannabis decreases headache and migraine ratings as well as whether gender, type of cannabis (concentrate vs. flower), THC, CBD, or dose contribute to changes in these ratings. 31715263 2019
Entrez Id: 54858
Gene Symbol: PGPEP1
PGPEP1
0.010 Biomarker group BEFREE The Migraine Disability Assessment (MIDAS), Patient Global Impression of Severity (PGI-S), Patient Global Impression of Improvement (PGI-I), and migraine headache days (MHD) served as anchors. 30861580 2019
Entrez Id: 11047
Gene Symbol: ADRM1
ADRM1
0.010 Biomarker group BEFREE Arm 1 comprised 33 216 patients with FM and arm 2 consisted of 7420 patients with migraine; all of these patients were diagnosed between 2000 and 2010. 30962236 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.010 Biomarker group BEFREE We found that administration of IFNγ-DC-Exos reduced susceptibility to spreading depression <i>in vivo</i> and <i>in vitro</i>, suggesting that IFNγ-DC-Exos may be a potential therapeutic for migraine. 31551696 2019
Entrez Id: 1066
Gene Symbol: CES1
CES1
0.010 Biomarker group BEFREE Outcome measures included migraine disability (using Migraine Disability Assessment tool [MIDAS]), headache self-efficacy (using Headache Management Self-Efficacy Scale [HMSE]), acute medication use, and migraine frequency. 31738274 2019
Entrez Id: 728458
Gene Symbol: OPN1MW2
OPN1MW2
0.010 Biomarker group BEFREE We sought to determine whether inhalation of cannabis decreases headache and migraine ratings as well as whether gender, type of cannabis (concentrate vs. flower), THC, CBD, or dose contribute to changes in these ratings. 31715263 2019
Entrez Id: 29108
Gene Symbol: PYCARD
PYCARD
0.010 GeneticVariation group BEFREE Kinesiophobia and clinical migraine features were not significantly associated (P > 0.05), nor were TSK score, ASC-12 score, or clinical migraine features (r < 0.21, P > 0.05). 30462312 2019
Entrez Id: 55301
Gene Symbol: OLAH
OLAH
0.010 GeneticVariation group BEFREE This prospective, double-blind, phase 3 multicentre study randomly assigned patients with migraine with and without aura (1:1:1:1 ratio) to oral lasmiditan 200 mg, 100 mg, 50 mg, or placebo. 31132795 2019
Entrez Id: 1525
Gene Symbol: CXADR
CXADR
0.010 Biomarker group BEFREE Although non-specific, serum NLR, MLR, PLR, and CAR levels may be potential biomarkers associated with migraine subtypes with different clinical features such as migraine attack period, migraine with aura, and patients with family history of migraine. 31758522 2019
Entrez Id: 55364
Gene Symbol: IMPACT
IMPACT
0.010 Biomarker group BEFREE Baseline ImPACT composite scores were similar between migraine and control groups (d = 0.04-0.13). 31842054 2019
Entrez Id: 494324
Gene Symbol: MIR375
MIR375
0.010 Biomarker group BEFREE Hsa-miR-34a-5p and hsa-miR-375 as Biomarkers for Monitoring the Effects of Drug Treatment for Migraine Pain in Children and Adolescents: A Pilot Study. 31252698 2019
Entrez Id: 54207
Gene Symbol: KCNK10
KCNK10
0.010 Biomarker group BEFREE These findings identify TREK1 and TREK2 as potential molecular targets in migraine and suggest that fsATI should be considered as a distinct class of mutations. 30573346 2019
Entrez Id: 10206
Gene Symbol: TRIM13
TRIM13
0.010 Biomarker group BEFREE Although non-specific, serum NLR, MLR, PLR, and CAR levels may be potential biomarkers associated with migraine subtypes with different clinical features such as migraine attack period, migraine with aura, and patients with family history of migraine. 31758522 2019
Entrez Id: 101060233
Gene Symbol: OPN1MW3
OPN1MW3
0.010 Biomarker group BEFREE We sought to determine whether inhalation of cannabis decreases headache and migraine ratings as well as whether gender, type of cannabis (concentrate vs. flower), THC, CBD, or dose contribute to changes in these ratings. 31715263 2019
Entrez Id: 2652
Gene Symbol: OPN1MW
OPN1MW
0.010 Biomarker group BEFREE We sought to determine whether inhalation of cannabis decreases headache and migraine ratings as well as whether gender, type of cannabis (concentrate vs. flower), THC, CBD, or dose contribute to changes in these ratings. 31715263 2019
Entrez Id: 55888
Gene Symbol: ZKSCAN7
ZKSCAN7
0.010 Biomarker group BEFREE History of migraine was associated with lower percentage of ZFP (SE=-0.0166) compared with no history of migraine in the superior peripapillary retina only (p<0.05). 31784501 2019
Entrez Id: 2821
Gene Symbol: GPI
GPI
0.010 Biomarker group BEFREE The Migraine Disability Assessment (MIDAS), Patient Global Impression of Severity (PGI-S), Patient Global Impression of Improvement (PGI-I), and migraine headache days (MHD) served as anchors. 30861580 2019
Entrez Id: 94233
Gene Symbol: OPN4
OPN4
0.010 Biomarker group BEFREE In this review, we briefly summarise the melanopsin system in the normal retina and discuss its role in connection to human aging (sleep/wake problems) and retinal pathology in Alzheimer and Parkinson diseases, diabetic retinopathy, mitochondrial optic neuropathies, glaucoma, retinitis pigmentosa, and in photophobia during migraine and in seasonal affective disorder (SAD). 31219170 2019