Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
0.010 GeneticVariation disease BEFREE In conclusion, the use of COX inhibitors was associated with a reduced risk of HCC in CHB. 31505085 2020
Entrez Id: 9377
Gene Symbol: COX5A
COX5A
0.010 GeneticVariation disease BEFREE In conclusion, the use of COX inhibitors was associated with a reduced risk of HCC in CHB. 31505085 2020
Entrez Id: 1371
Gene Symbol: CPOX
CPOX
0.010 GeneticVariation disease BEFREE In conclusion, the use of COX inhibitors was associated with a reduced risk of HCC in CHB. 31505085 2020
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
0.010 Biomarker disease BEFREE Furthermore, we also found that the serum sE-cadherin levels were significantly negatively correlated with TAC, antioxidant enzymes (GSH and SOD) in patients with CHB, and that serum sE-cadherin concentrations were significantly positively correlated with liver enzyme markers (alanine transaminase and aspartate aminotransferase) and oxidative markers (TOA, NOX2, and MDA) in patients with CHB. 31429942 2020
Entrez Id: 7431
Gene Symbol: VIM
VIM
0.010 AlteredExpression disease BEFREE The methylation frequencies of SOX1 and VIM promoters in HCC patients were significantly higher than those in LC (p<0.001 and p<0.001), CHB (p<0.001 and p<0.001) and HC (p<0.001 and p<0.001) subjects. 28592127 2019
Entrez Id: 8834
Gene Symbol: TMEM11
TMEM11
0.010 GeneticVariation disease BEFREE Postpartum cardiac events occurred in 9 pregnancies (14.3%) in 8 women with CAVB; 3 had cardiac failure and p-PMI, 3 had cardiac failure, 2 required p-PMI, and 1 had cardiopulmonary arrest. 31060956 2019
Entrez Id: 633
Gene Symbol: BGN
BGN
0.010 AlteredExpression disease BEFREE Positive correlation was found between fibrosis stages and BGN level of the CHB group (r=0.64; p<0.001) and between fibrosis stages and OPN level of the CHB (r=0.63; p<0.001) and CHC (r=0.59; p<0.03) groups. 30385593 2019
Entrez Id: 345
Gene Symbol: APOC3
APOC3
0.010 Biomarker disease BEFREE These data showed that HBV infection inhibits lipid metabolism and ApoC3 is negatively associated with HBV DNA load in HBeAg (-) CHB patients. 31186008 2019
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.010 AlteredExpression disease BEFREE Serum apolipoprotein C3 (ApoC3) and apolipoprotein A5 (ApoA5) levels were decreased in chronic hepatitis B (CHB) patients, however the relationship between ApoC3 or ApoA5 and HBV DNA load remains elusive. 31186008 2019
Entrez Id: 9771
Gene Symbol: RAPGEF5
RAPGEF5
0.010 GeneticVariation disease BEFREE The CHINAcr-cys equation may be more suitable for the estimation of GFR in Chinese patients with CHB or compensated cirrhosis. 30830657 2019
Entrez Id: 4351
Gene Symbol: MPI
MPI
0.010 GeneticVariation disease BEFREE Postpartum cardiac events occurred in 9 pregnancies (14.3%) in 8 women with CAVB; 3 had cardiac failure and p-PMI, 3 had cardiac failure, 2 required p-PMI, and 1 had cardiopulmonary arrest. 31060956 2019
Entrez Id: 115908
Gene Symbol: CTHRC1
CTHRC1
0.010 AlteredExpression disease BEFREE CTHRC1 expression was significantly increased in the PBC and PSC groups, compared with the HC and CHB groups. 31102333 2019
Entrez Id: 11035
Gene Symbol: RIPK3
RIPK3
0.010 AlteredExpression disease BEFREE We found that RIPK3 mRNA levels were significantly higher in patients with ACHBLF than those with CHB or HCs. 30996211 2019
Entrez Id: 23671
Gene Symbol: TMEFF2
TMEFF2
0.010 Biomarker disease BEFREE The use of SHG/TPEF-based image technology may give useful suggestive information in evaluation of CHB-related liver fibrosis for the short sample (biopsy length > 0.5 cm). 31187402 2019
Entrez Id: 51567
Gene Symbol: TDP2
TDP2
0.010 GeneticVariation disease BEFREE Here, we aimed to investigate the association of NTCP, FXRα, HNF1α, HNF4α, and TDP2 genetic polymorphisms with the natural course of CHB and antiviral treatment response. 31505315 2019
Entrez Id: 10344
Gene Symbol: CCL26
CCL26
0.010 AlteredExpression disease BEFREE Serum CCL11, CCL24 and CCL26 levels were significantly higher in PBC patients than those with CHB and HC (P < 0.05). 30583236 2019
Entrez Id: 25970
Gene Symbol: SH2B1
SH2B1
0.010 Biomarker disease BEFREE After PSM and GLM, the significant predictors for worsening renal function were age, hypertension and diabetes mellitus but not CHB, ETV or cirrhosis. 30460749 2019
Entrez Id: 10219
Gene Symbol: KLRG1
KLRG1
0.010 Biomarker disease BEFREE Patients with CHB had a higher frequency of KLRG1+ NK cells compared to healthy controls (blood 13.4 vs. 2.3%, p <0.0001 and liver 23.4 vs. 2.6%, p <0.01). 30905683 2019
Entrez Id: 2167
Gene Symbol: FABP4
FABP4
0.010 AlteredExpression disease BEFREE Low FGF-21 and high AFABP levels were associated with advanced fibrosis/cirrhosis in CHB patients on antiviral treatment. 30912255 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 Biomarker disease BEFREE Serum levels of SAA and CRP (C-reactive protein) were positively correlated in patients with CHB (<i>P</i> < 0.001), pyogenic liver abscess (<i>P</i> = 0.045), and active AILD (<i>P</i> = 0.02). 31798280 2019
Entrez Id: 5373
Gene Symbol: PMM2
PMM2
0.010 GeneticVariation disease BEFREE Postpartum cardiac events occurred in 9 pregnancies (14.3%) in 8 women with CAVB; 3 had cardiac failure and p-PMI, 3 had cardiac failure, 2 required p-PMI, and 1 had cardiopulmonary arrest. 31060956 2019
Entrez Id: 23452
Gene Symbol: ANGPTL2
ANGPTL2
0.010 AlteredExpression disease BEFREE As shown in our previous studies, ANGPTL2 expression positively correlates with liver fibrosis stages in chronic hepatitis B (CHB) patients. 31534368 2019
Entrez Id: 768097
Gene Symbol: HAR1B
HAR1B
0.010 AlteredExpression disease BEFREE The expression levels of HAR1A and HAR1B were significantly lower in the HCC group, compared with the CHB and LC groups (P <.01). 30304523 2019
Entrez Id: 768096
Gene Symbol: HAR1A
HAR1A
0.010 AlteredExpression disease BEFREE The expression levels of HAR1A and HAR1B were significantly lower in the HCC group, compared with the CHB and LC groups (P <.01). 30304523 2019
Entrez Id: 283131
Gene Symbol: NEAT1
NEAT1
0.010 AlteredExpression disease BEFREE The total NEAT1 expression was abnormally decreased in CHB patients as compared with healthy controls. 30924966 2019