Gene: KRAS ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.120 GeneticVariation phenotype BEFREE A significant association with dry skin and global cetuximab-related toxicity was observed for the KRAS-LCS6 (rs61764370) variant (p<0.05); carriers of the G allele (genotypes TG+GG) in the dominant model were observed to have a decreased susceptibility of developing dry skin (OR=0.287 [95%CI=0.119-0.695]). 27938998 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.120 GeneticVariation phenotype BEFREE 154 patients were enrolled (WT KRAS n = 86; mutant KRAS n = 59); most (98%) experienced integument-related toxicities (most commonly rash [42%], dry skin [40%] and acne [36%]). 23020584 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.120 Biomarker phenotype HPO