Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
0.010 Biomarker disease BEFREE Then, we found that RMP was bound up with the status of nodal and T stage which indicating that RMP may be related to the growth and malignant degree of EC. 31333787 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 AlteredExpression disease BEFREE The enhanced expression of the MDR1 gene may be involved in the acquisition of vindesine resistance in human esophageal cancer cells. 8052486 1994
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 Biomarker disease BEFREE In conclusion, we propose that ABCB1 might play a pivotal role in acquisition of taxane resistance and could be a promising target for treatment of patients with esophageal cancer after acquisition of taxane resistance. 27941276 2016
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 GeneticVariation disease BEFREE MDR1 haplotype frequencies in Japanese and Caucasian, and in Japanese patients with colorectal cancer and esophageal cancer. 16702732 2006
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 Biomarker disease BEFREE Targeting the Bcl-2 family and P-glycoprotein reverses paclitaxel resistance in human esophageal carcinoma cell line. 28441715 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 AlteredExpression disease BEFREE The purpose of the study was to investigate the change of drug-sensitivity and P-glycoprotein (P-gp) expression in ionization radiation-induced human esophageal cancer radioresistant cells. 22545578 2012
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 GeneticVariation disease BEFREE We examined the ABCB1 gene polymorphism C3435T to predict response and prognosis to neoadjuvant radiochemotherapy (cisplatin, 5-fluorouracil and 36 Gy) in locally advanced esophageal cancer patients. 21332314 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 Biomarker disease BEFREE Down-regulation of miR-27a could confer sensitivity of both P-glycoprotein-related and P-glycoprotein-non-related drugs on esophageal cancer cells, and might promote ADR-induced apoptosis, accompanied by increased accumulation and decreased releasing amount of ADR. 19960259 2010
Entrez Id: 340273
Gene Symbol: ABCB5
ABCB5
0.010 Biomarker disease BEFREE Effects of silencing the ATP-binding cassette protein E1 gene by electroporation on the proliferation and migration of EC109 human esophageal cancer cells. 25815591 2015
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
0.010 Biomarker disease BEFREE ABC Transporters and Their Role in the Neoadjuvant Treatment of Esophageal Cancer. 29543757 2018
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
0.020 AlteredExpression disease BEFREE Although the expression of MRP was predominant in esophageal cancer cell lines, expression of either or both of the genes was detected in all the cell lines tested. 8637212 1996
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
0.020 AlteredExpression disease BEFREE In conclusion, TET possesses a reversal effect on drug resistance in YES-2/DDP cells through downregulation of MRP1, and has the potential to be an adjunct to chemotherapy for esophageal cancer. 22941407 2012
Entrez Id: 89845
Gene Symbol: ABCC10
ABCC10
0.010 Biomarker disease BEFREE This study provides the first demonstration that miR-let-7g/i target ABCC10 and modulate DDP resistance in EC cell lines. 26655271 2016
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
0.010 AlteredExpression disease BEFREE With a goal of identifying relations between gene expression and response (mucosal or pathological) or survival in esophageal cancer patients (stages II to IV) receiving oxaliplatin, 5-fluorouracil (5FU) and radiation, we measured in endoscopic primary tumor biopsies from 38 patients, the expression of seven genes (gammaGCS, gammaGT, MRP-2, ERCC-1, XPA, TS and DPD) prior to treatment, 1 week following oxaliplatin alone and at the end of the combined radio-chemotherapy cycle using real time QRT-PCR. 17127229 2006
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
0.020 AlteredExpression disease BEFREE ABCE1 expression is low in the adjacent non-tumor tissues while the expression is high in the esophageal carcinoma; the expression is reversely proportional to the differentiation degrees. 24551278 2014
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
0.020 Biomarker disease BEFREE These results revealed that ABCE1 is closely associated with cell proliferation, invasion and migration in esophageal cancer and silencing the ABCE1 gene by electroporation can significantly reduce the proliferation, invasion and migration capacity of EC109 cells in vitro. 25815591 2015
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
0.030 AlteredExpression disease BEFREE The expression of linc-VLDLR and ABCG2 mRNA in 60 cases of esophageal carcinoma tissue, para-carcinoma tissue and the normal esophagus tissue were detected using Fluorescence quantitative reverse transcription polymerase chain reaction (qRT-PCR). 30606658 2019
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
0.030 Biomarker disease BEFREE The present study detected the correlation between ABCG2 and the multidrug resistance of esophageal cancer. 24535197 2014
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
0.030 Biomarker disease BEFREE After treatment of Eca109/ABCG2 (an esophageal cancer multidrug resistance cell line) cells with adriamycin (ADM) combined with EGCG for 24h, the cellular apoptosis, mitochondrial membrane potential, ADM concentration in cells and ABCG2 protein expression were detected by flow cytometry. 28964574 2017
Entrez Id: 25
Gene Symbol: ABL1
ABL1
0.010 Biomarker disease BEFREE ABL regulation by AXL promotes cisplatin resistance in esophageal cancer. 23117882 2013
Entrez Id: 28
Gene Symbol: ABO
ABO
0.020 GeneticVariation disease BEFREE Allele frequency of ABO blood group antigen and the risk of esophageal cancer. 25054136 2014
Entrez Id: 28
Gene Symbol: ABO
ABO
0.020 Biomarker disease BEFREE The distribution of ABO blood groups in patients with EC or CC was similar to the normal local population in Chaoshan. 11819849 2001
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
0.010 Biomarker disease BEFREE The effects of neoadjuvant therapy on morbidity and mortality of esophagectomy for esophageal cancer: American college of surgeons national surgical quality improvement program (ACS-NSQIP) 2005-2012. 27813095 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.010 Biomarker disease BEFREE An ACE insertion/deletion polymorphism might modulate the function of ACE gene and play a role in affecting individual susceptibility to pulmonary injury following esophagectomy in patients of esophageal cancer. 15798469 2005
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
0.010 Biomarker disease BEFREE Importantly, Interleukin 8 (IL8) and C-X-C chemokine receptor type 7 (CXCR-7) were predicted to be significantly related to EC. 29285246 2017