| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | In summary, the current study demonstrated that inhibition of BMI1 and Mel18 could increase the sensitivity of esophageal cancer cells to cisplatin via inhibition of c-Myc. | 31186712 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | BMI-1 suppression increases the radiosensitivity of oesophageal carcinoma via the PI3K/Akt signaling pathway. | 29207170 | 2018 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | The expression of Bmi-1 is associated with the progression and invasion of esophageal cancer. | 29240461 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | High expression of B-cell specific Moloney leukemia virus insert site 1 (Bmi-1) and peptidyl arginine deiminase IV (PADI4) is associated with esophageal carcinoma. | 28599437 | 2017 | ||||
|
0.090 | PosttranslationalModification | disease | BEFREE | Knockdown of BMI-1 expression decreased the phosphorylation of H2AX, upregulated p16, and induced the radiosensitivity of esophageal cancer ECA109 and TE13 cells in vitro and significantly inhibited the growth and invasion of tumor cells. | 27108688 | 2016 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | In Caucasian populations, high expression of Bmi-1 was associated with better OS in breast cancer (HR=0.70, 95% CI 0.51-0.97), but it showed no significance in oesophageal carcinoma. | 25458792 | 2014 | ||||
|
0.090 | Biomarker | disease | BEFREE | Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells. | 22842564 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | The presence of Bmi-1 autoantibodies in sera from patients with ESCC may have clinical utility in esophageal cancer diagnosis. | 20809956 | 2010 | ||||
|
0.090 | Biomarker | disease | BEFREE | These results suggest that Bmi-1 is a potential molecular target of treating esophageal cancer. | 20591222 | 2010 |