Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 Biomarker disease BEFREE To explore the anti-tumor effects of esophageal cancer-related gene 2 (ECRG2) in combination with cisplatin (DDP) in DDP-resistant esophageal cancer cells (EC9706/DDP). 28348485 2017
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 Biomarker disease BEFREE Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin. 24606472 2014
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 Biomarker disease BEFREE A short tandem repeat (STR) polymorphism in the 3'UTR region of esophageal cancer-related gene 2 (ECRG2, also known as SPINK7) has been widely reported to be associated with the incidence and the prognosis of esophageal squamous cell carcinoma (ESCC). 22315007 2013
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 Biomarker disease BEFREE Esophageal cancer-related gene 2 (ECRG2) is found to be critical in the process of carcinogenesis. 23079671 2012
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 AlteredExpression disease BEFREE However, ECRG2 gene was significantly down-regulated in primary esophageal cancer tissues. 21042721 2010
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 GeneticVariation disease BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of esophageal cancer related gene 2 (ECRG2) are a prognostic marker for squamous cell carcinoma (SCC) of the esophagus. 17418617 2008
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 GeneticVariation disease BEFREE In conclusion, the ECRG2 TCA (3)/TCA (4) genotype is associated with the risk of oesophageal carcinoma in a North Indian population. 18618216 2008
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 GeneticVariation disease BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of the Kazal-type esophageal cancer related gene (ECRG2) have been reported to be associated with esophageal carcinoma. 17352218 2007
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 GeneticVariation disease BEFREE Genetically fixed STR polymorphism TCA3/TCA3 in exon 4 of ECRG2 is associated with poor clinical outcome in surgically treated esophageal cancer patients and might be a potential prognostic marker. 17693286 2007
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 Biomarker disease BEFREE The esophageal cancer-related gene 2 (ECRG2) is a novel gene that shows sequence similarity to KAZAL-type serine protease inhibitor. 17602171 2007
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 GeneticVariation disease BEFREE Short tandem repeat polymorphism in a novel esophageal cancer-related gene (ECRG2) implicates susceptibility to esophageal cancer in Chinese population. 14639608 2004
Entrez Id: 84651
Gene Symbol: SPINK7
SPINK7
0.100 Biomarker disease BEFREE Transfection of ECRG2 gene inhibited cell proliferation and induced apoptosis in esophageal cancer cells. 12646258 2003