Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
0.010 AlteredExpression disease BEFREE In the present study, we found that β1-adrenoceptor (β1-AR) and β2-AR expression and the phosphorylation of the downstream molecule protein kinase A (PKA) were elevated in transplanted submandibular glands obtained from epiphora patients. 29358308 2018
Entrez Id: 29123
Gene Symbol: ANKRD11
ANKRD11
0.100 GeneticVariation disease CLINVAR
Entrez Id: 414
Gene Symbol: ARSD
ARSD
0.010 Biomarker disease BEFREE Cases of ARS with overlapping features with other ASD, like aniridia (complete or incomplete absence of iris), iridocorneal endothelial (ICE) syndrome (beaten metal appearance of corneal endothelium), Peters anomaly, isolated trabeculodysgenesis (evidenced by Haab's striae, buphthalmos, and epiphora) in one or both eyes with other typical ARS features in the same or other eye were included and screened. 27929720 2018
Entrez Id: 1308
Gene Symbol: COL17A1
COL17A1
0.100 Biomarker disease HPO
Entrez Id: 28960
Gene Symbol: DCPS
DCPS
0.010 Biomarker disease BEFREE Cases of ARS with overlapping features with other ASD, like aniridia (complete or incomplete absence of iris), iridocorneal endothelial (ICE) syndrome (beaten metal appearance of corneal endothelium), Peters anomaly, isolated trabeculodysgenesis (evidenced by Haab's striae, buphthalmos, and epiphora) in one or both eyes with other typical ARS features in the same or other eye were included and screened. 27929720 2018
Entrez Id: 1637
Gene Symbol: DCR
DCR
0.010 Biomarker disease BEFREE Twenty-two patients who had epiphora and recurrent dacryocystitis after at least a previous failed revision DCR as well as 22 patients receiving conventional EN-DCR only were enrolled in the study between January 2008 and December 2011. 28784098 2017
Entrez Id: 1736
Gene Symbol: DKC1
DKC1
0.100 Biomarker disease HPO
Entrez Id: 1736
Gene Symbol: DKC1
DKC1
0.100 GeneticVariation disease CLINVAR
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.100 Biomarker disease HPO
Entrez Id: 3321
Gene Symbol: IGSF3
IGSF3
0.100 Biomarker disease HPO
Entrez Id: 10265
Gene Symbol: IRX5
IRX5
0.300 Biomarker disease CTD_human Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1. 22581230 2012
Entrez Id: 3859
Gene Symbol: KRT12
KRT12
0.100 Biomarker disease HPO
Entrez Id: 3850
Gene Symbol: KRT3
KRT3
0.100 Biomarker disease HPO
Entrez Id: 4035
Gene Symbol: LRP1
LRP1
0.100 Biomarker disease HPO
Entrez Id: 26002
Gene Symbol: MOXD1
MOXD1
0.010 Biomarker disease BEFREE Instillation of MOX-HCl loaded in situ gel did not cause any type of irritation symptoms like redness, inflammation and excessive tear production in rabbits as compared to control. 31751751 2019
Entrez Id: 55651
Gene Symbol: NHP2
NHP2
0.100 Biomarker disease HPO
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
0.100 Biomarker disease HPO
Entrez Id: 55505
Gene Symbol: NOP10
NOP10
0.100 Biomarker disease HPO
Entrez Id: 100506658
Gene Symbol: OCLN
OCLN
0.010 Biomarker disease BEFREE Taken together, our findings suggest that decreased interaction between ZO-1 and occludin might contribute to the epiphora occurred in the transplanted SMGs, and mAChR together with the intracellular molecule CK2 might be responsible for the alteration of TJs in epiphora glands. 28332063 2017
Entrez Id: 58495
Gene Symbol: OVOL2
OVOL2
0.100 Biomarker disease HPO
Entrez Id: 5340
Gene Symbol: PLG
PLG
0.100 Biomarker disease HPO
Entrez Id: 6012
Gene Symbol: RIEG2
RIEG2
0.010 Biomarker disease BEFREE Cases of ARS with overlapping features with other ASD, like aniridia (complete or incomplete absence of iris), iridocorneal endothelial (ICE) syndrome (beaten metal appearance of corneal endothelium), Peters anomaly, isolated trabeculodysgenesis (evidenced by Haab's striae, buphthalmos, and epiphora) in one or both eyes with other typical ARS features in the same or other eye were included and screened. 27929720 2018
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
0.100 Biomarker disease HPO
Entrez Id: 64218
Gene Symbol: SEMA4A
SEMA4A
0.100 Biomarker disease HPO
Entrez Id: 57152
Gene Symbol: SLURP1
SLURP1
0.010 Biomarker disease BEFREE Cases of ARS with overlapping features with other ASD, like aniridia (complete or incomplete absence of iris), iridocorneal endothelial (ICE) syndrome (beaten metal appearance of corneal endothelium), Peters anomaly, isolated trabeculodysgenesis (evidenced by Haab's striae, buphthalmos, and epiphora) in one or both eyes with other typical ARS features in the same or other eye were included and screened. 27929720 2018