Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 53347
Gene Symbol: UBASH3A
UBASH3A
0.010 Biomarker disease BEFREE Mice lacking expression of the homologous phosphatases Sts-1 and Sts-2 (Sts<sup>-/-</sup> mice) are resistant to disseminated candidiasis caused by the fungal pathogen <i>Candida albicans</i> To better understand the immunological mechanisms underlying the enhanced resistance of Sts<sup>-/-</sup> mice, we examined the kinetics of fungal clearance at early time points.In contrast to the rapid <i>C. albicans</i> growth seen in normal kidneys during the first 24 h postinfection, we observed a reduction in kidney fungal CFU within Sts<sup>-/-</sup> mice beginning at 12 to 18 h postinfection. 30018105 2018