Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4050
Gene Symbol: LTB
LTB
0.010 Biomarker group BEFREE IL7, LTB and CXCL13, which was shown to be correlated with human oral cancer-associated TLSs. 31652350 2020
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.010 GeneticVariation group BEFREE This preliminary prospective study suggests that polymorphism of TGFBR1 rs334348 may act as a potentially independent factor and novel genetic biomarker to predict oral cancer DSS especially for patients with radiotherapy. 31651066 2020
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
0.010 GeneticVariation group BEFREE We observed five SNPs-rs2051526 (ETV6), rs6021247 (NFATC2), rs3757769 (SND1), rs7085532 (TCF7L2), and rs7778413 (SND1) indicating increased oral cancer risk with OR ranging from 1.61 to 34.60. 31452252 2020
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
0.010 GeneticVariation group BEFREE We observed five SNPs-rs2051526 (ETV6), rs6021247 (NFATC2), rs3757769 (SND1), rs7085532 (TCF7L2), and rs7778413 (SND1) indicating increased oral cancer risk with OR ranging from 1.61 to 34.60. 31452252 2020
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3
0.010 Biomarker group BEFREE MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a. 31771044 2020
Entrez Id: 6487
Gene Symbol: ST3GAL3
ST3GAL3
0.010 AlteredExpression group BEFREE Higher mRNA levels of ST3GAL2 and ST3GAL3 were significantly associated with advanced stage of the disease, lymph node involvement and perineural invasion, which denote their role in progression and metastasis of oral cancer. 31747460 2020
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4
0.010 Biomarker group BEFREE To investigate a possible role for DNA nucleotide repair proteins in oral cancer behavior, this study evaluated the immunoexpression of the proteins TFIIH and XPF and its association with clinical, histological, and survival parameters in oral tongue squamous-cell carcinoma (OTSCC). 31828418 2020
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
0.010 GeneticVariation group BEFREE We observed five SNPs-rs2051526 (ETV6), rs6021247 (NFATC2), rs3757769 (SND1), rs7085532 (TCF7L2), and rs7778413 (SND1) indicating increased oral cancer risk with OR ranging from 1.61 to 34.60. 31452252 2020
Entrez Id: 4162
Gene Symbol: MCAM
MCAM
0.010 AlteredExpression group BEFREE CD146 expression in oral lichen planus and oral cancer. 31102047 2020
Entrez Id: 3574
Gene Symbol: IL7
IL7
0.010 Biomarker group BEFREE IL7, LTB and CXCL13, which was shown to be correlated with human oral cancer-associated TLSs. 31652350 2020
Entrez Id: 27044
Gene Symbol: SND1
SND1
0.010 GeneticVariation group BEFREE We observed five SNPs-rs2051526 (ETV6), rs6021247 (NFATC2), rs3757769 (SND1), rs7085532 (TCF7L2), and rs7778413 (SND1) indicating increased oral cancer risk with OR ranging from 1.61 to 34.60. 31452252 2020
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
0.010 Biomarker group BEFREE It was found that the expression of miR-155 is abnormally elevated in oral cancer tissues, suggesting that miR-155 may be a tumor-promoting gene for oral cancer. 31771044 2020
Entrez Id: 6483
Gene Symbol: ST3GAL2
ST3GAL2
0.010 AlteredExpression group BEFREE Higher mRNA levels of ST3GAL2 and ST3GAL3 were significantly associated with advanced stage of the disease, lymph node involvement and perineural invasion, which denote their role in progression and metastasis of oral cancer. 31747460 2020
Entrez Id: 10197
Gene Symbol: PSME3
PSME3
0.010 Biomarker group BEFREE Proteasome activator 28γ (PA28γ) upregulation plays a critical role in the carcinogenesis of many malignancies, including oral cancer. 31605415 2020
Entrez Id: 10563
Gene Symbol: CXCL13
CXCL13
0.010 Biomarker group BEFREE IL7, LTB and CXCL13, which was shown to be correlated with human oral cancer-associated TLSs. 31652350 2020
Entrez Id: 3043
Gene Symbol: HBB
HBB
0.010 GeneticVariation group BEFREE Thus in the current study, we assessed the association of thirteen SNPs in seven transcription factor genes along with HBB (a control SNP) to identify high-risk genotypes associated with increased oral cancer risk in an Indian cohort of tobacco habitués. 31452252 2020
Entrez Id: 328
Gene Symbol: APEX1
APEX1
0.010 GeneticVariation group BEFREE However, APE1 polymorphisms did not significantly correlate with development of oral cancer in the case-control study and logistic regression analysis. 30652382 2019
Entrez Id: 10507
Gene Symbol: SEMA4D
SEMA4D
0.010 Biomarker group BEFREE Treatment of tumor-bearing mice with Sema4D mAb abrogated Ly6G<sup>hi</sup> PMN-MDSC recruitment through reducing MAPK-dependent chemokine production by tumor cells in Murine oral cancer-1 (MOC1) tumors. 30514791 2019
Entrez Id: 574448
Gene Symbol: MIR202
MIR202
0.010 Biomarker group BEFREE Receiver operating characteristic analysis was carried out to explore the diagnostic value of serum miR-202 for oral cancer. 31258685 2019
Entrez Id: 619554
Gene Symbol: MIR486-1
MIR486-1
0.010 Biomarker group BEFREE This study was the first to demonstrate that betel nut alkaloid may recruit DNMT3B to regulate miR-486-3p/DDR1 axis in oral cancer andmiR-486-3p and DDR1 may serve as potential therapeutic targets of oral cancer. 31253192 2019
Entrez Id: 2744
Gene Symbol: GLS
GLS
0.010 AlteredExpression group BEFREE c-Myc overexpression promotes oral cancer cell proliferation and migration by enhancing GLS and GS activity. 31324362 2019
Entrez Id: 5250
Gene Symbol: SLC25A3
SLC25A3
0.010 Biomarker group BEFREE The qualitative results confirmed that high-performance OHTs tend to emphasize oral cancer surveillance and deliver prostheses in PHC services. 31145771 2019
Entrez Id: 1300
Gene Symbol: COL10A1
COL10A1
0.010 Biomarker group BEFREE We aimed at investigating if human bone marrow mesenchymal stem cells (hBMSCs)-derived exosomes affect oral cancer development, and the potential regulatory mechanism associated with COL10A1 and miR-101-3p. 31165315 2019
Entrez Id: 100302142
Gene Symbol: MIR1246
MIR1246
0.010 Biomarker group BEFREE Our previous work has demonstrated that non-coding RNA miR-1246 contributes to the cancer stemness of oral cancer. 30928188 2019
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
0.010 Biomarker group BEFREE Thus, the present study evaluated the contribution of CHI3L1 SNPs to oral cancer susceptibility and clinicopathology. 30341592 2019