| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | group | BEFREE | Correlation of Inflammatory Markers, Survival, and COX2 Expression in Oral Cancer and Implications for Prognosis. | 29359615 | 2018 | ||||
|
0.090 | GeneticVariation | group | BEFREE | On the other hand, 1195 A > G (rs689466) polymorphism in COX-2 did not confer susceptibility to oral cancers. | 25977924 | 2015 | ||||
|
0.090 | Biomarker | group | BEFREE | PGE2 production in oral cancer cell lines is COX-2-dependent. | 19278989 | 2009 | ||||
|
0.090 | AlteredExpression | group | BEFREE | COX-2 expression in oral cancer was found to be independent of grade of tumor and stage of disease. | 18356024 | 2008 | ||||
|
0.090 | AlteredExpression | group | BEFREE | In conclusion, this study demonstrates correlation between over expression of NF-kappaB and COX-2 in early precancerous stages of development of oral cancer and sustained elevation down the tumorigenic pathway, underscoring their potential as targets for early intervention. | 17354234 | 2007 | ||||
|
0.090 | AlteredExpression | group | BEFREE | We measured COX-1 and COX-2 m-RNA expression in samples of both oral cancer and matched oral mucosa from 22 patients by RealTime RT-PCR; clinic pathological data (grading, TNM staging, inflammation, follow-up) of all patients were available for statistical evaluation. | 17624243 | 2007 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. | 17595767 | 2007 | ||||
|
0.090 | Biomarker | group | BEFREE | Molecular targeting of COX-2, PGE(2) synthase, or PGE(2) receptors may be useful as a chemopreventive or therapeutic strategy for oral cancer. | 12738747 | 2003 | ||||
|
0.090 | AlteredExpression | group | BEFREE | COX-2 expression was correlated to DNA content as a genetic risk marker of oral cancer. | 12747975 | 2003 |