| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | group | BEFREE | Migration is regulated by EP4/PI3K/Orai1 signaling in oral cancer. | 31755615 | 2020 | ||||
|
0.090 | Biomarker | group | BEFREE | Mutational status of PIK3ca oncogene in oral cancer-In the new age of PI3K inhibitors. | 31831300 | 2020 | ||||
|
0.090 | Biomarker | group | BEFREE | Targeted disruption of PI3K/Akt/mTOR signaling pathway, via PI3K inhibitors, promotes growth inhibitory effects in oral cancer cells. | 30519710 | 2019 | ||||
|
0.090 | Biomarker | group | BEFREE | Oridonin inhibits oral cancer growth and PI3K/Akt signaling pathway. | 29432993 | 2018 | ||||
|
0.090 | Biomarker | group | BEFREE | Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancer. | 30352996 | 2018 | ||||
|
0.090 | AlteredExpression | group | BEFREE | Crosstalk between Raf-MEK-ERK and PI3K-Akt-GSK3β signaling networks promotes chemoresistance, invasion/migration and stemness via expression of CD44 variants (v4 and v6) in oral cancer. | 30409306 | 2018 | ||||
|
0.090 | Biomarker | group | BEFREE | Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance. | 23806066 | 2013 | ||||
|
0.090 | AlteredExpression | group | BEFREE | We observed significantly higher PI3K p110α (p<0.0001) and lower (p<0.0001) vesicular sorting protein 34p (Vps34p) mRNA both in PBMC and tissue samples of oral cancer patients as compared to the normal controls. | 23228846 | 2013 | ||||
|
0.090 | Biomarker | group | BEFREE | We also discussed how targeting the Akt and MEK, downstream effectors of the PI3K/Akt and MAPK pathways, respectively, would probably pave the possible molecular therapeutic target for the ras driven tumorigenesis in oral cancer. | 22240207 | 2012 |