Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
0.010 Biomarker disease BEFREE We found preoperative CEA serum values to correlate with peritoneal cancer index. 27038681 2016
Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7
0.010 Biomarker disease BEFREE We found preoperative CEA serum values to correlate with peritoneal cancer index. 27038681 2016
Entrez Id: 1429
Gene Symbol: CRYZ
CRYZ
0.010 GeneticVariation disease BEFREE Clinical significance of a NAD(P)H: quinone oxidoreductase 1 polymorphism in patients with disseminated peritoneal cancer receiving intraperitoneal hyperthermic chemotherapy with mitomycin C. 11773862 2002
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
0.010 Biomarker disease BEFREE Clinical pathways of recovery after surgery for advanced ovarian/tubal/peritoneal cancer: an NSGO-MaNGO international survey in collaboration with AGO-a focus on surgical aspects. 30640702 2019
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.010 Biomarker disease BEFREE We demonstrated that HGF secreted by ovarian cancer cells plays an important role in cancer peritoneal implantation. 26335595 2015
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.010 AlteredExpression disease BEFREE Ad-mIL-10 treatment increased intraperitoneal IL-10 levels until 3 weeks after treatment, and then significantly inhibited peritoneal cancer growth by inhibiting angiogenesis. 17992202 2008
Entrez Id: 90865
Gene Symbol: IL33
IL33
0.010 Biomarker disease BEFREE Direct peritoneal administration of IL-33 delayed the progression of metastatic peritoneal cancer. 30546956 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.010 Biomarker disease BEFREE We previously reported that KRAS promoted tumorigenesis and increased neutrophil counts in a mouse peritoneal cancer model. 30066851 2018
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
0.010 Biomarker disease BEFREE A MEK inhibitor was used to evaluate the effect on cancer peritoneal dissemination. 30509235 2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
0.010 Biomarker disease BEFREE Altogether, our data suggest that exosomal miR-21-5p induces MMT of PMCs and promote cancer peritoneal dissemination by targeting SMAD7. 30154401 2018
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
0.010 GeneticVariation disease BEFREE The finding of only one case of post-operative peritoneal cancer in 220 carriers undergoing RRBSO supports the discontinuation of post-RRBSO serum CA125 monitoring in BRCA mutation carriers. 24389956 2014
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
0.010 GeneticVariation disease BEFREE The purpose of our study was to determine the effect of the 609C>T polymorphism on tumor NQO1 activity and overall survival in patients with disseminated peritoneal cancer receiving intraperitoneal mitomycin C therapy. 11773862 2002
Entrez Id: 5225
Gene Symbol: PGC
PGC
0.010 GeneticVariation disease BEFREE We characterized the N- and O-glycome of serous ovarian (OC) and peritoneal cancer (PC) tissues using PGC-LC-ESI-IT-MS/MS profiling and validated the discriminatory glycans and their corresponding glyco-gene expression levels using cell lines and transcriptomic data from 232 patients. 28853212 2017
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
0.010 Biomarker disease BEFREE We found preoperative CEA serum values to correlate with peritoneal cancer index. 27038681 2016
Entrez Id: 7010
Gene Symbol: TEK
TEK
0.010 Biomarker disease BEFREE We aimed to assess whether trebananib, a peptibody that inhibits binding of angiopoietin 1 and 2 to Tie2, improved progression-free survival when added to carboplatin and paclitaxel as first-line therapy in advanced epithelial ovarian, primary fallopian tube, or peritoneal cancer in a phase 3 clinical trial. 31076365 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.010 Biomarker disease BEFREE We investigated the hypothesis that this autocrine action of TNF-alpha generates and sustains a network of other mediators that promote peritoneal cancer growth and spread. 17234767 2007
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
0.010 GeneticVariation disease BEFREE In case of a peritoneal cancer index (PCI) score >20, CRS-HIPEC is not considered to be beneficial. 31818845 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.010 AlteredExpression disease BEFREE We determined if nintedanib, a tyrosine kinase inhibitor of VEGF, FGF, and PDGF receptors has antitumor activity in bevacizumab-resistant recurrent EOC, tubal, and peritoneal cancer. 30929823 2019