Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 AlteredExpression disease BEFREE Also, MMP-3 levels in patients with AMI carrying 5A/5A were elevated compared with those carrying 6A/6A. 26712881 2016
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 GeneticVariation disease BEFREE There are significant differences in MMP-3 '5A' allele and genotype in the patients with AMI comparing with controls. 20616708 2010
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 GeneticVariation disease BEFREE The 5A allele of the MMP3 5A/6A polymorphism was associated with acute myocardial infarction (odds ratio (OR) 1.26, 95% confidence interval (CI) 1.1 to 1.4, p<0.001), suggesting its role in plaque rupture. 16905683 2006
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 Biomarker disease BEFREE Together with previous findings, these results primarily implicate MMP-3 in atherosclerosis progression rather than in acute MI. 16629857 2006
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 GeneticVariation disease BEFREE We can conclude that there was a significant association between the 5A/6A polymorphism in the promoter region of stromelysin-1 gene and young MI in Taiwan. 12876636 2003
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 Biomarker disease BEFREE Matrix metalloproteinases, such as stromelysin-1, are implicated in the pathogenesis of coronary artery disease (CAD) and acute myocardial infarction (MI). 12515907 2002
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.070 GeneticVariation disease BEFREE Moreover, The 5A/6A polymorphism in the promoter region of the stromelysin-1 gene may be a pathogenetic risk factor for acute myocardial infarction. 12205736 2002