Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE miR-1, miR-499 and miR-208 are sensitive markers to diagnose sudden death due to early acute myocardial infarction. 31240830 2019
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 AlteredExpression disease BEFREE In mice, we find that AMI is accompanied by an increase in circulating levels of myo-miRs, with miR-1, 208, and 499 predominantly in circulating exosomes and miR-133 in the non-exosomal component. 30814518 2019
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE Selected microRNAs (miR-1, miR-133a, and miR-499) were measured in a cohort of 122 patients from the PRAGUE-18 study (ticagrelor vs. prasugrel in AMI treated with primary percutaneous coronary intervention (pPCI)). 31781298 2019
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 AlteredExpression disease BEFREE Circulating miR-1 level was significantly higher in AMI group than in non-AMI group (P < 0.001). 31611081 2019
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE Following the identification of cardiac-specific microRNA miR-208a in circulation, more non-coding RNAs (miR-1, miR-499 and miR-133) have been identified as biomarkers not only for the diagnosis of AMI but also for prognosis post infarction. 29698386 2018
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE This may be that miR-1 is reported as a biomarker of acute myocardial infarction. 30319429 2018
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 AlteredExpression disease BEFREE Mir-1 and miR-29b plasma levels post-AMI correlate with IV changes. 28663047 2017
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE In particular, miR-133a/b (5 studies), miR-208a/b (6 studies), and miR-499 (7 studies) were well studied and found to be significant diagnostic and/or prognostic markers across different cardiovascular disease progression stages. miR-1 and miR-145b are potential biomarkers of ACS; miR-1 with higher sensitivity for all acute myocardial infarction (AMI), and miR-145 for STEMI and worse outcome of AMI. 27357636 2016
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE Although miR-1 and miR-208b decreased (1.4-fold) and increased (1.2-fold), respectively, in the AMI samples compared to the controls, the significance of these changes was limited by our sample size. 26046358 2015
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE For biological validation, RNA from 12 representative probands, extracted with all 6 kits (n = 72), was reverse transcribed and mRNAs (matrix metalloproteinase 9, arginase 1) and miRNAs (miR133a, miR1), shown to be altered by AMI, were analyzed. 25469788 2014
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 Biomarker disease BEFREE Our results demonstrate that circulating miR-1, -133a, -208b, and -499 may be useful biomarkers in acute myocardial infarction patients but that these miRNAs are not superior to cardiac troponin T for the diagnosis of acute myocardial infarction. 23420161 2013
Entrez Id: 83856
Gene Symbol: FSD1L
FSD1L
0.100 AlteredExpression disease BEFREE Serum levels of miRNA (miR)-1 and miR-133a were increased significantly in patients not only with acute myocardial infarction but also with unstable angina pectoris and Takotsubo cardiomyopathy without elevation of serum creatine phosphokinase or cardiac troponin. 21642241 2011