Gene: ABCA1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		0.050 Biomarker phenotype BEFREE Sortilin promotes macrophage cholesterol accumulation and aortic atherosclerosis through lysosomal degradation of ATP-binding cassette transporter A1 protein. 30950489 2019
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		0.050 Biomarker phenotype BEFREE Our results revealed that Tan IIA promotes cholesterol efflux and ameliorates lipid accumulation in macrophages most likely via the Omentin-1/ABCA1 pathway, reducing the development of aortic atherosclerosis. 30947667 2019
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		0.050 Biomarker phenotype BEFREE The present study demonstrates that Dgn enhances ABCA1-dependent cholesterol efflux and inhibits aortic atherosclerosis progression by suppressing macrophage miR-19b expression. 25765596 2015
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		0.050 Biomarker phenotype BEFREE As expected from the pro-atherogenic plasma lipid profile, aortic atherosclerosis was increased 10-fold in ABCA1-Tg mice. 16928680 2006
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		0.050 Biomarker phenotype BEFREE These beneficial changes in the lipid profile led to significantly lower (65%) aortic atherosclerosis in hABCA1-Tg mice. 11752403 2002