Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.060 | AlteredExpression | disease | BEFREE | Correlation analysis demonstrated that an elevated CAR was markedly correlated with the tumor size (P = .019), alpha-fetoprotein (AFP) level (P = .033), thrombosis of the portal vein (P = .004), the NLR (P = .036), and the LMR (P = .001). | 31418936 | 2019 | ||||
|
0.060 | Biomarker | disease | BEFREE | In conclusion, we proposed noninvasive criteria that could accurately differentiate tumor PVT from bland PVT called A-VENA, which is based on the presence of ≥3 of the following: AFP >1000 ng/dL; venous expansion; thrombus enhancement; neovascularity; and adjacent to HCC. | 30246323 | 2019 | ||||
|
0.060 | Biomarker | disease | BEFREE | For patients treated with TACE, higher alpha-fetoprotein (hazard ratio 1.11 per doubling, P=.008) and segmental portal vein thrombosis (hazard ratio 9.9, P<.001) were associated with worse LC. | 29066120 | 2018 | ||||
|
0.060 | AlteredExpression | disease | BEFREE | Additionally, NEK2 overexpression was also associated with pretreatment serum AFP level (OR =1.79; 95% CI: 1.23-2.61; <i>P</i><0.01) and portal vein thrombosis (OR =2.74; 95% CI: 1.22-6.17; <i>P</i>=0.01) in hepatocellular carcinoma. | 30425509 | 2018 | ||||
|
0.060 | AlteredExpression | disease | BEFREE | Tumor size (>5 cm), multinodularity, elevated serum AFP (>20 ng/mL) level, Child-Turcotte-Pugh score (B and C), and portal vein thrombosis were significant factors for OS. | 28208001 | 2017 | ||||
|
0.060 | AlteredExpression | disease | BEFREE | A large HCC patient cohort was retrospectively examined, and the possible relationships of albumin levels to tumor diameter, multifocality, portal vein thrombosis (PVT) and α-fetoprotein levels were examined. | 28862714 | 2017 |