Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.330 Biomarker disease BEFREE 7-9-month old wild-type and secreted protein acidic and rich in cysteine (SPARC)-null (a model of disc degeneration and LBP) male mice were treated with TAK-242 (TLR4 inhibitor) once, and following a 10-day washout, mice were treated 3 times/week for 8 weeks. 29908959 2018
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.330 GeneticVariation disease BEFREE Inactivation of the SPARC gene in mice results in premature intervertebral disc degeneration. 20714283 2011
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.330 PosttranslationalModification disease BEFREE In parallel, we show that human subjects with back pain exhibit signs of disc degeneration and increased methylation of the SPARC promoter. 21867537 2011
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
0.330 Biomarker disease CTD_human Inactivation of the SPARC gene in mice results in premature intervertebral disc degeneration. 20714283 2011