Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 Biomarker disease BEFREE Since tooth agenesis is commonly found in individuals with cleft lip/palate (CL/P), we used four large cohorts to evaluate if IRF6 and TGFA interaction contributes to CL/P. 23029012 2012
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE MTHFR, TGFB3, and TGFA polymorphisms and their association with the risk of non-syndromic cleft lip and cleft palate in China. 20082468 2010
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 AlteredExpression disease BEFREE Therefore, based on this study, it is not possible to determine the role played by TGFA in the expression of cleft lip and palate. 18788876 2008
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE Transforming growth factor-alpha (TGFA) was the first gene suggested to be associated with nonsyndromic cleft lip, cleft palate, or both (CL/ P). 15222785 2004
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 Biomarker disease BEFREE Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA, we included TGFA in the analysis as well. 15329380 2004
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE Thus it is concluded that TGF genes play a role in craniofacial development, and that alleles of TGFalpha or/and TGFbeta2 are associated with cleft lip and cleft palate in Japanese populations. 10918043 2000
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE Association between alleles of the transforming growth factor alpha locus and cleft lip and palate in the Chilean population. 7573126 1995
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE Genetic variation in transforming growth factor alpha: possible association of BamHI polymorphism with bilateral sporadic cleft lip and palate. 8103504 1993
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE Confirmation of an association between RFLPs at the transforming growth factor-alpha locus and non-syndromic cleft lip and palate. 1352354 1992
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate. 1352355 1992
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 Biomarker disease BEFREE These findings indicate that CLP and TGFA are not tightly linked in these families. 1679292 1991
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.100 GeneticVariation disease BEFREE Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate. 2570526 1989