×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
Biomarker
disease
BEFREE
Since tooth agenesis is commonly found in individuals with cleft lip/palate (CL/P), we used four large cohorts to evaluate if IRF6 and TGFA interaction contributes to CL/P.
23029012
2012
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
MTHFR, TGFB3, and TGFA polymorphisms and their association with the risk of non-syndromic cleft lip and cleft palate in China.
20082468
2010
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
AlteredExpression
disease
BEFREE
Therefore, based on this study, it is not possible to determine the role played by TGFA in the expression of cleft lip and palate .
18788876
2008
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
Transforming growth factor-alpha (TGFA ) was the first gene suggested to be associated with nonsyndromic cleft lip, cleft palate , or both (CL/ P).
15222785
2004
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
Biomarker
disease
BEFREE
Since cleft lip/palate is also associated with both tooth agenesis and the gene TGFA , we included TGFA in the analysis as well.
15329380
2004
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
Thus it is concluded that TGF genes play a role in craniofacial development, and that alleles of TGFalpha or/and TGFbeta2 are associated with cleft lip and cleft palate in Japanese populations.
10918043
2000
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
Association between alleles of the transforming growth factor alpha locus and cleft lip and palate in the Chilean population.
7573126
1995
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
Genetic variation in transforming growth factor alpha : possible association of BamHI polymorphism with bilateral sporadic cleft lip and palate .
8103504
1993
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
Confirmation of an association between RFLPs at the transforming growth factor-alpha locus and non-syndromic cleft lip and palate .
1352354
1992
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate .
1352355
1992
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
Biomarker
disease
BEFREE
These findings indicate that CLP and TGFA are not tightly linked in these families.
1679292
1991
×
Entrez Id:
7039
Gene Symbol:
TGFA
TGFA
0.100
GeneticVariation
disease
BEFREE
Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate .
2570526
1989