Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE Genetic variants in the human androgen receptor gene (AR) are associated with male pattern baldness (androgenetic alopecia, AGA) in Europeans. 19373488 2009
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE The results suggest this form of genomic variation at the AR locus is unlikely to predispose to AGA. 19340294 2009
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE The one man in seven who harbors risk alleles at both 20p11.22 and AR (encoding the androgen receptor) has a sevenfold-increased odds of androgenic alopecia (OR = 7.12, P = 3.7 x 10(-15)). 18849991 2008
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE Baldness and the androgen receptor: the AR polyglycine repeat polymorphism does not confer susceptibility to androgenetic alopecia. 17256155 2007
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE To test whether partial loss of function in the AR gene associated with CAG polymorphism reduces the risk of AGA in affected men. 17596176 2007
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 Biomarker disease CTD_human We demonstrate that genetic variability in the androgen receptor gene (AR) is the cardinal prerequisite for the development of early-onset AGA, with an etiological fraction of 0.46. 15902657 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE We demonstrate that genetic variability in the androgen receptor gene (AR) is the cardinal prerequisite for the development of early-onset AGA, with an etiological fraction of 0.46. 15902657 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 AlteredExpression disease BEFREE Expression of androgen receptor coactivator ARA70/ELE1 in androgenic alopecia. 16115056 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE The CAG and GGC repeats in the AR have been studied extensively as markers of prostate cancer susceptibility, with inconclusive findings, whereas the AR-E211 G>A polymorphism has been associated with androgenetic alopecia. 15824176 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.400 GeneticVariation disease BEFREE Androgen receptor polymorphisms (CAG repeat lengths) in androgenetic alopecia, hirsutism, and acne. 9677254 1998
Entrez Id: 387
Gene Symbol: RHOA
RHOA 		0.300 Biomarker disease CTD_human Postzygotic inactivating mutations of RHOA cause a mosaic neuroectodermal syndrome. 31570889 2019
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		0.300 Biomarker disease CTD_human PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal. 29367455 2018
Entrez Id: 23476
Gene Symbol: BRD4
BRD4 		0.300 Biomarker disease CTD_human Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition. 25242322 2014
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.300 Biomarker disease CTD_human Hairless modulates ligand-dependent activation of the vitamin D receptor-retinoid X receptor heterodimer. 22466564 2012
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker disease CTD_human CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice. 21359208 2011
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13 		0.300 Biomarker disease CTD_human Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. 20548961 2010
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		0.300 Biomarker disease CTD_human Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. 20561897 2010
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1 		0.300 Biomarker disease CTD_human Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. 19145458 2009
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A 		0.300 Biomarker disease CTD_human Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study. 19652058 2009
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		0.300 Biomarker disease CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker disease CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794 2008
Entrez Id: 55806
Gene Symbol: HR
HR 		0.300 Biomarker disease CTD_human A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu. 16455232 2006
Entrez Id: 7538
Gene Symbol: ZFP36
ZFP36 		0.300 Biomarker disease CTD_human Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function. 15944294 2005
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.300 Biomarker disease CTD_human [Vitamin D-resistant rickets type II: apropos of 2 cases]. 1338926 1992
Entrez Id: 80326
Gene Symbol: WNT10A
WNT10A 		0.110 GeneticVariation disease GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017