In the present study, STMN1 mRNA levels were significantly higher (p < 0.05) in ACC patients, especially in an advanced stage, and correlated with BUB1B and PINK1 expression, the prognostic-related genes in ACC.
Finally, <i>G0S2</i> methylation combined with validated molecular markers (<i>BUB1B-PINK1</i>) stratifies ACC into three groups, with uniformly favorable, intermediate, and uniformly dismal outcomes.