Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.350 Biomarker disease BEFREE Vaccination with a co-expression DNA plasmid containing GAD65 fragment gene and IL-10 gene induces regulatory CD4(+) T cells that prevent experimental autoimmune diabetes. 26797873 2016
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.350 Biomarker disease BEFREE Application of this therapeutic tool achieved gut mucosal delivery of a diabetes-relevant autoantigen and a biologically active immunomodulatory cytokine, IL-10, and, when combined with a low dose of systemic anti-CD3, was well tolerated and induced autoantigen-specific long-term tolerance, allowing reversal of established autoimmune diabetes. 22484814 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.350 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.350 Biomarker disease BEFREE Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice. 18779928 2009
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.350 Biomarker disease BEFREE Our results prove a minor role of IL-10 in the autoimmune diabetes risk, although we found the same association trend with IL-10G(*)12 allele as was previously observed for multiple sclerosis and rheumatoid arthritis. 15057267 2004
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.350 AlteredExpression disease BEFREE The combined administration of interleukin-4 (IL-4) and interleukin-10 (IL-10) expression plasmids has demonstrated synergistic effects on the prevention of autoimmune diabetes. 12628339 2003