Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.310 GeneticVariation disease BEFREE The diagnostic subgroups of tuberous sclerosis complex were not correlated with BRAF(V600E) in patients with SEGA (P = 0.533). 25346165 2015
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.310 AlteredExpression disease BEFREE Expression of EGF, EGFR, HGF, c-Met, and VEGF protein, as well as hypoxia inducible factor-1α, a transcription factor that regulates VEGF levels and is also modulated by mTOR cascade activity, was enhanced in SEGAs (n = 6) and tubers (n = 10) from 15 TSC patients. 21224066 2011
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.310 Biomarker disease CTD_human Agonists of the retinoic acid- and retinoid X-receptors inhibit hepatocyte growth factor secretion and expression in U87 human astrocytoma cells. 11223164 2001
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
0.310 Biomarker disease CTD_human Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers. 15341671 2004
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.310 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.310 Biomarker disease BEFREE Expression of EGF, EGFR, HGF, c-Met, and VEGF protein, as well as hypoxia inducible factor-1α, a transcription factor that regulates VEGF levels and is also modulated by mTOR cascade activity, was enhanced in SEGAs (n = 6) and tubers (n = 10) from 15 TSC patients. 21224066 2011
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 4763
Gene Symbol: NF1
NF1
0.300 Biomarker disease CTD_human Bioluminescent approaches for measuring tumor growth in a mouse model of neurofibromatosis. 20176786 2010
Entrez Id: 367
Gene Symbol: AR
AR
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 57670
Gene Symbol: KIAA1549
KIAA1549
0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.300 Biomarker disease CTD_human Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. 23817572 2013
Entrez Id: 4233
Gene Symbol: MET
MET
0.300 Biomarker disease CTD_human Agonists of the retinoic acid- and retinoid X-receptors inhibit hepatocyte growth factor secretion and expression in U87 human astrocytoma cells. 11223164 2001
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
0.300 Biomarker disease CTD_human Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. 24705250 2014
Entrez Id: 23462
Gene Symbol: HEY1
HEY1
0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 9113
Gene Symbol: LATS1
LATS1
0.300 Biomarker disease CTD_human Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. 17049657 2006
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
0.300 Biomarker disease CTD_human Expression of estrogen receptors, androgen receptor and steroid receptor coactivator-3 is negatively correlated to the differentiation of astrocytic tumors. 24680642 2014
Entrez Id: 26524
Gene Symbol: LATS2
LATS2
0.300 Biomarker disease CTD_human Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. 17049657 2006
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
0.300 Biomarker disease CTD_human Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. 20188714 2010
Entrez Id: 23493
Gene Symbol: HEY2
HEY2
0.300 Biomarker disease CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.300 Biomarker disease CTD_human Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. 20188714 2010