Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE α-Fetoprotein as a predictor of outcome for children with germ cell tumors: A report from the Malignant Germ Cell International Consortium. 31355926 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE Yolk sac tumors (YSTs) are malignant germ cell tumors that secrete alpha-fetoprotein (AFP). 30985686 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE Background Measurement of α-fetoprotein (AFP) concentrations in the serum of infants is useful for the management of testicular germ cell tumors, hepatoblastoma and hepatocellular carcinoma. 30367785 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE Persistently elevated alpha-fetoprotein associated with chronic hepatitis B during chemotherapy for malignant ovarian germ cell tumors: a case series and a review of the literature. 31836006 2019
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE Although immunohistochemical examination is not always needed in routine for the diagnosis of clear cell type EOC, to distinguish from other tumors, especially germ cell tumors, or to provide the better way to monitor therapeutic response or to evaluate the disease status, immunostaining, including GPC3, HNF-1 beta, CD30, cytokeratin 7 or 20, and AFP is taken into account. 29933751 2018
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 AlteredExpression disease BEFREE Preoperative serum alpha-fetoprotein (AFP) levels were reviewed in germ cell tumor (GCT) cases and analyzed to predict malignancy in various age groups. 28967388 2017
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE The prognostic information provided by alpha-fetoprotein and human chorionic gonadotrophin in the management of germ cell tumor (GCT) patients is a biochemical reflection of tumor differentiation. 12860944 2003
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE By establishing sensitive nested reverse transcription-PCRs for the detection of mRNA of alpha-fetoprotein (AFP) and beta human chorionic gonadotropin (betahCG), we investigated the presence of circulating tumor cells in the peripheral blood of 119 patients with germ-cell tumor. 10866307 2000
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE Thus, AFP in germ cell tumors is explained by the development of the yolk sac visceral endoderm (YSVE) in teratocarcinomas, since YSVE is the first site of AFP synthesis in the embryo. 10202131 1999
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE Hereditary persistence of alpha-fetoprotein (HPAFP) should be considered in both children and adults with unexplained and persistent elevation of AFP e.g., those screened for hepatocellular carcinoma or diagnosed for germ cell tumor. 9681083 1998
Entrez Id: 174
Gene Symbol: AFP
AFP
0.100 Biomarker disease BEFREE We recommend that all males with KS and early sexual development or with "normal" testicular growth be screened with measurement of germ cell tumor markers including beta-subunit of human chorionic gonadotropin and alpha-fetoprotein. 7535510 1995