100 female syndrome X (60 +/- 9 years), 100 female CHD (65 +/- 9 years) and 100 healthy female volunteers (61 +/- 10 years) completed the hospital anxiety and depression scale (HADS), health anxiety questionnaire (HAQ), a demographic information scale, life events scale, family history of CHD, menopausal, menstrual and gynaecological history.A 17beta-oestradiol sample was taken.