×
Entrez Id:
1628
Gene Symbol:
DBP
DBP
0.010
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP : diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP: systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
×
Entrez Id:
6822
Gene Symbol:
SULT2A1
SULT2A1
0.020
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS : dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP: systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
×
Entrez Id:
6046
Gene Symbol:
BRD2
BRD2
0.050
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH : follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP: systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
×
Entrez Id:
6462
Gene Symbol:
SHBG
SHBG
0.100
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP : systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
×
Entrez Id:
5120
Gene Symbol:
PCOS1
PCOS1
0.020
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO : polycystic ovaries; PCO : polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP: systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
×
Entrez Id:
54535
Gene Symbol:
CCHCR1
CCHCR1
0.010
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP : systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
SELENBP1
0.010
Biomarker
disease
BEFREE
<b>Abbreviations</b>: AUC: area under curve; BMI: body mass index; C: cholesterol; CI: confidence interval; DBP: diastolic blood pressure; DHEAS: dehydroepiandrosterone sulfate; FG: Ferriman-Gallway; FSH: follicle stimulating hormone; GHQ: general health questionnaire; HA: hyperandrogenism ; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostatic model assessment for insulin resistance; HWR: hip waist ratio; LDL-C: low-density lipoprotein cholesterol; LH: luteinizing hormone; LH: luteinizing hormone; LHR: lutropin receptor; O: oligomenorrhea; OR: odds ratio; PCO: polycystic ovaries; PCO: polycystic ovary; PCOS: polycystic ovary syndrome; PCR: polymerase chain reaction; ROC: receiver operating curve; SBP : systolic blood pressure; SE: standard error of coefficient; SNP: single nucleotide polymorphism; TG: triglycerides; TSH: thyroid stimulating hormone; VD: vitamin D.
30958034
2019
×
Entrez Id:
366
Gene Symbol:
AQP9
AQP9
0.010
Biomarker
disease
BEFREE
Hyperandrogenism in FF of women with PCOS inhibited AQP-9 in GCs through the PI3K pathway.
20378617
2010
×
Entrez Id:
367
Gene Symbol:
AR
AR
0.080
GeneticVariation
disease
BEFREE
Androgen receptor gene CAG repeat polymorphism in the development of ovarian hyperandrogenism .
12843184
2003
×
Entrez Id:
3569
Gene Symbol:
IL6
IL6
0.030
Biomarker
disease
BEFREE
Interleukin-6 (IL-6 ), is an inflammatory cytokine that may influence the pathogenesis of obesity and hyperandrogenism .
12917504
2003
×
Entrez Id:
3640
Gene Symbol:
INSL3
INSL3
0.010
Biomarker
disease
LHGDN
INSL3 could be considered a new circulating hormone related to LH-dependent ovarian hyperandrogenism , particularly in normal-weight PCOS women.
17356050
2007
×
Entrez Id:
2492
Gene Symbol:
FSHR
FSHR
0.010
GeneticVariation
disease
BEFREE
FSHR Ser(680) was associated with higher levels of gonadotrophic hormones (FSH: P < 0.01, LH: P = 0.01), and testosterone (P = 0.05) and a higher frequency of hyperandrogenism (P = 0.04).
19403562
2009
×
Entrez Id:
9370
Gene Symbol:
ADIPOQ
ADIPOQ
0.020
AlteredExpression
disease
BEFREE
Adiponectin gene polymorphisms were not associated with the anthropometric parameters, hyperandrogenism and adiponectin levels in PCOS.
20388053
2010
×
Entrez Id:
6662
Gene Symbol:
SOX9
SOX9
0.010
AlteredExpression
disease
BEFREE
SOX9 was expressed in the granulosa cell nucleus in 2/6 cases but also in 9/24 tumors without hyperandrogenism (p=n.s.).
20395670
2010
×
Entrez Id:
668
Gene Symbol:
FOXL2
FOXL2
0.010
Biomarker
disease
BEFREE
FOXL2 was absent or decreased in 3/6 cases of JGCTO with hyperandrogenism with no statistical difference from the group without this symptom.
20395670
2010
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.240
Biomarker
disease
RGD
Peroxisome proliferator-activated receptor gamma and early folliculogenesis during an acute hyperandrogenism condition.
20813360
2011
×
Entrez Id:
5468
Gene Symbol:
PPARG
PPARG
0.240
Biomarker
disease
BEFREE
PPARγ are receptors that are probably involved in hyperandrogenism .
21827375
2012
×
Entrez Id:
2353
Gene Symbol:
FOS
FOS
0.010
Biomarker
disease
BEFREE
FOS dysfunction may be a common factor between hyperandrogenism and insulin resistance.
22723319
2012
×
Entrez Id:
268
Gene Symbol:
AMH
AMH
0.090
Biomarker
disease
BEFREE
AMH was cross-sectionally and longitudinally related to hyperandrogenism .
28432801
2017
×
Entrez Id:
4880
Gene Symbol:
NPPC
NPPC
0.010
Biomarker
disease
BEFREE
C-type natriuretic peptide : a link between hyperandrogenism and anovulation in a mouse model of polycystic ovary syndrome.
29739821
2018
×
Entrez Id:
1393
Gene Symbol:
CRHBP
CRHBP
0.010
AlteredExpression
disease
BEFREE
Corticotropin releasing hormone binding protein is consistently the up-regulated lncRNA with the highest fold-change in PCOS-T compared with either control or PCOS-N . Gene ontology and pathway analysis showed that dysregulated lncRNA in PCOS-T have a regulatory role in mitochondrial function by interacting with transcription factors such as YY1 and SIX5.
30224242
2018
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
0.050
Biomarker
disease
BEFREE
TNF α , pro-inflammatory cytokine is associated with obesity, insulin resistance and hyperandrogenism , therefore in present study we tried to find the association between TNF α promoter polymorphisms, TNF α levels and the risk of PCOS.
30442458
2019
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
0.060
Biomarker
disease
BEFREE
POMC has also been identified as one of the candidate loci for polycystic ovary syndrome (PCOS) which features hyperandrogenism and some prevalence of obesity in patients.
31237951
2019
×
Entrez Id:
3643
Gene Symbol:
INSR
INSR
0.080
GeneticVariation
disease
BEFREE
A novel insulin receptor mutation in an adolescent with acanthosis nigricans and hyperandrogenism .
27505086
2016
×
Entrez Id:
659
Gene Symbol:
BMPR2
BMPR2
0.310
Biomarker
disease
BEFREE
A positive correlation was found between BMPR2 transcripts and hyperandrogenism in FF of PCOS patients.
22825968
2012