Gene: TP53 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.040 Biomarker disease BEFREE Chromosome 17 loss correlates well with previous descriptions of frequent allelic loss of 17p (TP53) in E-RMS. 10719362 2000
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.040 GeneticVariation disease BEFREE In patient 1, the normal p53 gene was lost while the mutant p53 allele was reduced to homozygosity in the RMS. 11494139 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.040 GeneticVariation disease BEFREE These studies show that absence of members of the dystrophin-associated glycoprotein complex constitutes a permissive environment for spontaneous development of embryonal RMS associated with mutation of p53 and mutation or altered splicing of Mdm2. 20019182 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.040 Biomarker disease BEFREE Conversely, p53 loss in maturing myoblasts gives rise to eRMS, which have the highest myodifferentiation potential. 21316601 2011