Gene: YAP1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 Biomarker disease CTD_human For instance, an upregulation of the Hpo downstream effector Yes-Associated Protein 1 (YAP) leads to the development of embryonal rhabdomyosarcoma (eRMS) in murine activated muscle satellite cells. 31494105 2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 Biomarker disease BEFREE For instance, an upregulation of the Hpo downstream effector Yes-Associated Protein 1 (YAP) leads to the development of embryonal rhabdomyosarcoma (eRMS) in murine activated muscle satellite cells. 31494105 2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 GeneticVariation disease BEFREE However, YAP1 is rarely mutated in human ERMS. 30353028 2018
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 Biomarker disease BEFREE A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma. 28923841 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 Biomarker disease BEFREE The Hippo effector YAP has recently been identified as a potent driver of embryonal rhabdomyosarcoma (ERMS). 27184927 2016
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 Biomarker disease BEFREE To interrogate the temporal contribution of YAP in eRMS tumorigenesis, we used a primary human cell-based genetic model of Ras-driven RMS. 26496700 2015
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		0.360 Biomarker disease BEFREE Collectively, our results identify YAP1 as a potent ERMS oncogenic driver and a promising target for differentiation therapy. 25087979 2014