Gene: TNFRSF8 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 Biomarker disease BEFREE Expression of CD30 has been observed in testicular cancers, and patients with CD30-expressing embryonal carcinomas have worse progression-free survival and overall survival than those with CD30-negative tumors. 29222199 2018
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 Biomarker disease BEFREE Brentuximab vedotin abrogates cell viability of CD30-positive GCT27 EC line exerting marked time-dependent antiproliferative and pro-apoptotic activity. 28941150 2018
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 AlteredExpression disease BEFREE CD30+ has a limited expression in normal cells but is the defining marker for embryonal carcinoma. 29236132 2018
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 Biomarker disease BEFREE Overall, these data suggest that CD30.CAR T cells might be useful as an immunotherapy for ECs. 30087115 2018
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 Biomarker disease BEFREE A total of 34/43 (79%) of difficult-to-classify areas stained 3+ for OCT3/4, CD30, and SOX2, similar to embryonal carcinoma. 19396148 2009
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 AlteredExpression disease BEFREE The present study was conducted to evaluate the expression patterns of OCT4 and CD30 in postchemotherapy metastatic embryonal carcinomas and to compare their utility as diagnostic tools. 16733205 2006
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.070 AlteredExpression disease BEFREE Antibodies with CD30 cross-linking activity failed to promote the growth of multipotent EC cell line GCT 27 X-1. 9111512 1997