Gene: NOTCH1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.050 Biomarker disease BEFREE We used retroviral vectors to overexpress active forms of NOTCH1, the NOTCH1 intracellular domain (N1ICD) and N1ICD that lacks the RBP-J-associated module (RAM), in human CCA cell lines RMCCA-1 and HuCCA-1. 30264361 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.050 AlteredExpression disease BEFREE In nude mice, corilagin suppressed cholangiocarcinoma growth and downregulated the expression of Notch1 and mammalian target of rapamycin. 31546767 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.050 Biomarker disease BEFREE Depletion of FBXW7 resulted in NOTCH1 accumulation and increased cholangiocarcinoma cell migration and self-renewal. 30302867 2018
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.050 Biomarker disease BEFREE In summary, we show that xanthohumol significantly reduced cholangiocarcinoma growth through the Notch1/AKT signaling axis. 29152142 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.050 AlteredExpression disease BEFREE Notch-1, but not other Notch receptors, were up-regulated by cholangiocytes in primary sclerosing cholangitis and cholangiocarcinoma. 15887117 2005