Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | GeneticVariation | disease | BEFREE | Patients with conventional epithelioid hemangioendothelioma with WWTR1-CAMTA1 fusion had a less favorable outcome compared with the YAP1-TFE3 subset, the 5-year overall survival being 59% versus 86%, respectively. | 31537895 | 2019 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | A recurrent YAP1-TFE3 gene fusion has been identified in WWTR1-CAMTA1-negative epithelioid hemangioendotheliomas arising in soft tissue, bone, and lung, but not in liver. | 28585251 | 2017 | ||||
|
0.370 | Biomarker | disease | BEFREE | EHEs have been characterized by tumor-specific WW domain-containing transcription regulator 1(WWTR1)-calmodulin-binding transcription activator 1 (CAMTA1) translocations, and recently, a novel Yes-associated protein 1 (YAP1)-transcription factor E3 (TFE3) gene fusion was identified in EHEs. | 26840265 | 2016 | ||||
|
0.370 | Biomarker | disease | BEFREE | Instead, WWTR1-CAMTA1 and YAP1-TFE3 fusion genes are found in almost all cases of epithelioid haemangioendothelioma. | 26050962 | 2015 | ||||
|
0.370 | Biomarker | disease | BEFREE | In addition, a recurrent YAP1-TFE3 gene fusion has been identified in WWTR1-CAMTA1 negative epithelioid hemangioendotheliomas. | 25680571 | 2015 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | This study confirms the high incidence of WWTR1-CAMTA1 and YAP1-TFE3 rearrangements in EHE and indicates that the staining pattern for TFE3 IHC is critical for specificity. | 25817592 | 2015 | ||||
|
0.370 | FusionGene | disease | ORPHANET | Epithelioid Hemangioendothelioma: clinicopathologic, immunhistochemical, and molecular genetic analysis of 39 cases. | 24986479 | 2014 | ||||
|
0.370 | GeneticVariation | disease | BEFREE | YAP1 gene rearrangements were then confirmed in seven of the remaining nine TFE3-rearranged EHEs by FISH. | 23737213 | 2013 |