Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | group | BEFREE | Subsequently, the pancreatic lesion was excised, and pathology assessment confirmed the diagnosis of well-differentiated neuroendocrine tumour with high expression of glucagon compatible with glucagonoma. | 31401568 | 2019 | ||||
|
0.070 | Biomarker | group | BEFREE | The accurate diagnosis of LHS requires the identification of the pancreatic primary as well as its correct classification as acinar because a variety of pancreatic tumors can be associated with skin lesions, ranging from rare metastasis of adenocarcinoma to the necrolytic migratory erythema caused by glucagon-producing neuroendocrine tumors. | 31300257 | 2019 | ||||
|
0.070 | Biomarker | group | BEFREE | Gastroenteropancreatic (GEP) NETs originate from the diffuse neuroendocrine system of the gastrointestinal tract and pancreatic islets cells: These tumors may produce many non-specific and specific substances, such as chromogranin A, insulin, gastrin, glucagon, and serotonin, which shape the clinical manifestations of the NETs. | 31382663 | 2019 | ||||
|
0.070 | Biomarker | group | BEFREE | Glucagonoma is an extremely rare, glucagon-secreting neuroendocrine tumor of the pancreas. | 29432346 | 2018 | ||||
|
0.070 | AlteredExpression | group | BEFREE | We report the effects of everolimus on gastrin and glucagon levels in patients with progressive pNET in RADIANT-1 (a single-arm phase II trial) and RADIANT-3 (a placebo-controlled, randomized, phase III trial). | 28609362 | 2017 | ||||
|
0.070 | Biomarker | group | BEFREE | Gastrointestinal peptide hormone receptors overexpressed in neuroendocrine tumors (NET), such as somatostatin or glucagon-like peptide-1 (GLP-1) receptors, are used for in vivo tumor targeting. | 22112810 | 2012 | ||||
|
0.070 | AlteredExpression | group | BEFREE | Total pancreatoduodenectomy was performed and conventional histopathologic examination revealed a well-differentiated cystic neuroendocrine tumor of the pancreas expressing glucagon and accompanied by several microadenomas. | 18520436 | 2008 |