Methylenetetrahydrofolate reductaseC677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
Influence of methylenetetrahydrofolate reductase gene polymorphisms on the outcome of pediatric patients with non-Hodgkin lymphoma treated with high-dose methotrexate.
The aim of this study was to investigate the genetic polymorphisms in 5, 10-methylenetetrahydrofolate reductase (MTHFR677C/T and 1298A/C) and to evaluate its associations with the risk of Non Hodgkin lymphoma.
This is the first reported case of intracardiac thrombosis with MTHFRA1298C and factor XIII V34L mutations together with granulomatous reaction in non-Hodgkin lymphoma.