Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE ALK(-) CD30(+) anaplastic large cell lymphoma is a type of non-Hodgkin lymphoma showing poor prognosis, and seldom co-occurs with sarcoidosis. 30909793 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Systemic anaplastic lymphoma kinase positive (ALK+) anaplastic large cell lymphoma with extranodal involvement (ALCL-E) is a rare form of non-Hodgkin lymphoma. 29602182 2018
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Anaplastic lymphoma kinase (ALK)-negative anaplastic large-cell lymphoma (ALCL) is a rare type of highly malignant, non-Hodgkin lymphoma. 29758012 2018
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL) is a rare distinct type of non-Hodgkin's lymphoma that arises in association with alterations of the ALK gene. 27686567 2017
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Anaplastic large cell lymphoma expressing anaplastic lymphoma kinase (ALK+ ALCL) is a distinct subtype of non-Hodgkin lymphoma. 29035291 2017
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Notably, ALK was initially discovered as the fusion gene in anaplastic large cell non-Hodgkin lymphoma, a disease predominantly of childhood. 26503946 2016
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Anaplastic lymphoma kinase (ALK) has emerged as an important oncogene in a number of human malignancies ranging from non-Hodgkin lymphoma to neuroblastoma. 22086496 2013
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE ALK-positive anaplastic large cell lymphoma (ALK+ ALCL) is an uncommon non-Hodgkin's lymphoma of T-cell origin, the majority of which express CD4 and show frequent pan-T-cell antigen loss. 21763080 2011
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 GeneticVariation disease BEFREE Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase, initially identified through the analysis of a specific translocation associated with a rare subtype of non-Hodgkin's lymphoma. 21205076 2011
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 GeneticVariation disease BEFREE Here we show that the anaplastic lymphoma kinase (ALK), originally identified as a fusion kinase in a subtype of non-Hodgkin's lymphoma (NPM-ALK) and more recently in adenocarcinoma of lung (EML4-ALK), is also a frequent target of genetic alteration in advanced neuroblastoma. 18923524 2008
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 GeneticVariation disease BEFREE The NPM-ALK fusion gene, formed by the t(2;5)(p23;q35) translocation in non-Hodgkin's lymphoma, encodes a 75-kDa hybrid protein that contains the amino-terminal 117 amino acid residues of the nucleolar phosphoprotein nucleophosmin (NPM) joined to the entire cytoplasmic portion of the receptor tyrosine kinase ALK (anaplastic lymphoma kinase). 9121481 1997
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 GeneticVariation disease BEFREE Detection of the t(2;5)(p23;q35) and NPM-ALK fusion in non-Hodgkin's lymphoma by two-color fluorescence in situ hybridization. 9057650 1997
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 GeneticVariation disease BEFREE ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK) 9174053 1997
Entrez Id: 238
Gene Symbol: ALK
ALK
0.100 Biomarker disease BEFREE Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. 8122112 1994