Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3558
Gene Symbol: IL2
IL2
0.060 AlteredExpression disease BEFREE (3) Immune reconstitution with HAART and immunostimulatory cytokines such as interleukin-2 (IL-2) and IL-12, combined with drugs that downregulate the replication or gene expression of tumor-associated viruses such as Epstein-Barr virus (EBV) and human herpes virus-8 (HHV-8), possibly in combination, should remain a primary goal in the treatment of HIV-NHL. 10950372 2000
Entrez Id: 5783
Gene Symbol: PTPN13
PTPN13
0.010 Biomarker disease BEFREE 5-Azacitidine induces demethylation of PTPL1 and inhibits growth in non-Hodgkin lymphoma. 26133246 2015
Entrez Id: 7750
Gene Symbol: ZMYM2
ZMYM2
0.010 GeneticVariation disease BEFREE 8p11 myeloproliferative syndrome (EMS) is a hematopoietic stem cell disorder characterized by myeloid hyperplasia and non-Hodgkin's lymphoma with chromosomal translocations fusing several genes, most commonly ZNF198, to fibroblast growth factor receptor-1 (FGFR1). 15050920 2004
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
0.010 GeneticVariation disease BEFREE 8p11 myeloproliferative syndrome (EMS) is a hematopoietic stem cell disorder characterized by myeloid hyperplasia and non-Hodgkin's lymphoma with chromosomal translocations fusing several genes, most commonly ZNF198, to fibroblast growth factor receptor-1 (FGFR1). 15050920 2004
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.010 AlteredExpression disease BEFREE Non-Hodgkin lymphoma expressing high levels of the danger-signalling protein HMGB1. 18569640 2008
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. 28840502 2018
Entrez Id: 894
Gene Symbol: CCND2
CCND2
0.010 GeneticVariation disease BEFREE Cyclin D2 promoter disrupted by t(12;22)(p13;q11.2) during transformation of chronic lymphocytic leukaemia to non-Hodgkin's lymphoma. 10460609 1999
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
0.030 AlteredExpression disease BEFREE Oncoprotein MDM2 overexpression is associated with poor prognosis in distinct non-Hodgkin's lymphoma entities. 10574597 1999
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.010 GeneticVariation disease BEFREE BRAF mutations in non-Hodgkin's lymphoma. 14612909 2003
Entrez Id: 2209
Gene Symbol: FCGR1A
FCGR1A
0.010 AlteredExpression disease BEFREE CD64 surface expression on neutrophils and monocytes is significantly up-regulated after stimulation with granulocyte colony-stimulating factor during CHOP chemotherapy for patients with non-Hodgkin's lymphoma. 14979480 2004
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.100 GeneticVariation disease BEFREE Tumor necrosis factor and lymphotoxin alfa genetic polymorphisms and outcome in pediatric patients with non-Hodgkin's lymphoma: results from Berlin-Frankfurt-Münster Trial NHL-BFM 95. 16293872 2005
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95. 16463153 2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.010 GeneticVariation disease BEFREE TGF-beta1 gene polymorphisms influence the course of the disease in non-Hodgkin's lymphoma patients. 16524740 2006
Entrez Id: 595
Gene Symbol: CCND1
CCND1
0.070 GeneticVariation disease BEFREE Cyclin D1 splice variant and risk for non-Hodgkin lymphoma. 16783567 2006
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 Biomarker disease BEFREE Bcl-2 has been implicated in conferring resistance to chemotherapy in non-Hodgkin's lymphoma and is therefore a candidate prognostic marker in DLBCL. 16796775 2006
Entrez Id: 947
Gene Symbol: CD34
CD34
0.030 Biomarker disease BEFREE CD34+ and Lin- cells were enriched from peripheral blood stem cell (PBSCs) grafts of patients with non-Hodgkin's lymphoma. 16797410 2006
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.030 GeneticVariation disease BEFREE Vitamin D receptor gene polymorphisms and risk of non-Hodgkin's lymphoma. 17650449 2007
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA
0.010 GeneticVariation disease BEFREE CEBPA polymorphisms and mutations in patients with acute myeloid leukemia, myelodysplastic syndrome, multiple myeloma and non-Hodgkin's lymphoma. 18182175 2008
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 GeneticVariation disease BEFREE Interleukin-10 gene polymorphisms influence the clinical course of non-Hodgkin's lymphoma. 18201362 2008
Entrez Id: 958
Gene Symbol: CD40
CD40
0.030 Biomarker disease BEFREE TNFRSF5 and TNFSF5 SNPs were examined in a population-based case-control study of non-Hodgkin lymphoma (376 cases/801 controls with DNA), and compelling findings were followed up in 2 independent populations. 18287517 2008
Entrez Id: 5347
Gene Symbol: PLK1
PLK1
0.030 Biomarker disease BEFREE Polo-like kinase 1 as a new target for non-Hodgkin's lymphoma treatment. 18547964 2008
Entrez Id: 2214
Gene Symbol: FCGR3A
FCGR3A
0.050 GeneticVariation disease BEFREE FCGR3A-158V/F polymorphism may correlate with the levels of immunoglobulin in patients with non-Hodgkin's lymphoma after rituximab treatment as an adjuvant to autologous stem cell transplantation. 19018870 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 GeneticVariation disease BEFREE TP53 mutations in circulating free DNA from Egyptian patients with non-Hodgkin's lymphoma. 19046801 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
0.070 GeneticVariation disease BEFREE Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma. 19391036 2009
Entrez Id: 338339
Gene Symbol: CLEC4D
CLEC4D
0.020 Biomarker disease BEFREE MCL is a rare entity of non-Hodgkin lymphoma, hitherto considered incurable. 19562619 2009