Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 GeneticVariation disease BEFREE Polymorphisms in DNA repair genes and MDR1 and the risk for non-Hodgkin lymphoma. 24756092 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 GeneticVariation disease BEFREE A phase I/II trial was performed to investigate the safety and tolerance of zosuquidar.3HCL, a potent inhibitor of P-glycoprotein (P-gp), when administered orally alone and in combination with the CHOP regimen in patients with untreated non-Hodgkin's lymphoma and to determine whether zosuquidar.3HCL affects pharmacokinetics of doxorubicin and vincristine. 17454628 2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 AlteredExpression disease BEFREE Our results show that P-gp is expressed before treatment of non-Hodgkin's lymphoma of HIV patients, and is related to poor response to treatment and overall survival. 17157997 2007
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 Biomarker disease BEFREE Preliminary results suggest that some haematological malignancies, among which are acute myelocytic leukaemia, multiple myeloma and non-Hodgkin's lymphoma, might benefit from the simultaneous administration of cytotoxic drugs and P-glycoprotein inhibitors. 7765326 1993
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 AlteredExpression disease BEFREE Expression of P-glycoprotein and anionic glutathione S-transferase genes in non-Hodgkin's lymphoma. 8094105 1993
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 Biomarker disease BEFREE Recent data, particularly in haematological malignancies such as acute non-lymphocytic leukaemia, myeloma and non-Hodgkin's lymphoma, indicate that P-glycoprotein may be involved in the development of clinical drug resistance. 1674435 1991
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
0.070 AlteredExpression disease BEFREE No mdr1 expression was detected in 5 out of 6 of these samples, whereas a low level of mdr1 expression was found in a sample from one PLL patient in the course of transformation to non-Hodgkin's lymphoma. 2323839 1990