| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | The MYC oncogene is dysregulated in approximately 30% of liver cancer. | 30833661 | 2019 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Considering the possibility that MYC may amplify the expression of PPARA target genes to potentiate cell proliferation and liver cancer, gene expression was analyzed from livers of wild-type and liver-specific Myc knockout (Myc<sup>ΔHep</sup> ) mice treated with the PPARA agonist pirinixic acid. | 30697791 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | In conclusion, we present an oncogenic role of FAM83H in liver cancer, which is closely associated with the oncogene MYC. | 28607447 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer. | 28273073 | 2017 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Amplification-dependent overexpression of 64 known driver oncogenes were found in 587 tumors (40%); genes frequently observed were MYC (25%) and MET (18%) in colorectal cancer; SKP2 (21%) in lung squamous cell carcinoma; HIST1H3B (19%) and MYCN (13%) in liver cancer; KIT (57%) in gastrointestinal stromal tumors; and FOXL2 (12%) in squamous cell carcinoma across tissues. | 28377632 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc. | 26513297 | 2015 | ||||
|
0.090 | Biomarker | disease | BEFREE | Therapeutic interventions, which would simultaneously target signaling pathways governing both DLC1 and MYC functions in hepatocarcinogenesis, could result in progress in the treatment of liver cancer. | 22580498 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer. | 22653869 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | We performed a forward genetic screen with a mouse model of MYC-induced liver cancer using SB-mediated mutagenesis. | 22556267 | 2012 |