×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
AlteredExpression
disease
BEFREE
Correlation between expression levels of PTEN and p53 genes and the clinical features of HBsAg-positive liver cancer .
28952211
2019
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN /PI3K/AKT Pathway in Liver Cancer .
31801250
2019
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
This strategy may overcome the disadvantages of naked Ad5-PTEN and enhance the antitumor effect on liver cancer .
29467932
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
Total Flavonoids from <i>Oroxylum indicum</i> Induce Apoptosis via PI3K/Akt/PTEN Signaling Pathway in Liver Cancer .
29636773
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
AlteredExpression
disease
BEFREE
HULC is negatively associated with expression of PTEN or miR15a in patients of human liver cancer .
29895332
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
PTEN gene has guiding significance in predicting the occurrence, development and prognosis of liver cancer .
30405802
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
Here, we have shown that deletion of both PTEN and SAV1 in the liver accelerates the development of NAFLD and liver cancer in mice.
29400692
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
Ablation of PTEN or Hippo pathway components induces liver cancer in a murine model by hyperactive AKT or YAP/TAZ, respectively.
29699606
2018
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
A recombinant adenovirus carrying the tumor suppressor gene PTEN (Ad5-PTEN ) is an effective antitumor agent against liver cancer .
28522194
2017
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
SHP2 and PTEN deficiencies were detected in liver cancer patients with poor prognosis.
27974211
2016
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
This study aimed to investigate the effect of overexpressing the phosphatase and tensin homolog deleted on chromosome 10 (PTEN ) gene on liver cancer cell apoptosis and provide new insight into the treatment of this disease.
27173355
2016
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
Herein, we demonstrate excessive CUDR cooperates with excessive CyclinD1 or PTEN depletion to accelerate liver cancer stem cells growth and liver stem cell malignant transformation in vitro and in vivo.
26513297
2015
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
AlteredExpression
disease
BEFREE
Besides, miRNA-32 down-regulates PTEN through binding to 3'-UTR of PTEN mRNA from luciferase reporter assay, and the expression level of miR-32 could affect the proliferation, migration, and invasion of liver cancer cell lines via PTEN/Akt signaling pathway.
25647261
2015
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
GeneticVariation
disease
BEFREE
Association of PTEN gene polymorphisms with liver cancer risk.
26823866
2015
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
Biomarker
disease
BEFREE
Mutation or deletion of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is strongly correlated with human liver cancer .
24027047
2014
×
Entrez Id:
5728
Gene Symbol:
PTEN
PTEN
0.100
AlteredExpression
disease
BEFREE
Recently, we have found that HBx causes the progression of liver cancer through down-expression of PTEN , known as a tumor suppressor gene (1).
15132991
2004