Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 Biomarker disease BEFREE The present study hypothesized that the use of SIgA vaccines or IL-6 inhibitors may be useful for reversing the immune deficiency associated with DCs in oral cancer. 28454394 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 Biomarker disease BEFREE Salivary IL-8, IL-6 and TNF-α as Potential Diagnostic Biomarkers for Oral Cancer. 28397778 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 AlteredExpression disease BEFREE In this study, quantitative expression level of IL-6 and VEGF in CAF and Oral Cancer Cells (OCCs) examined through Real Time PCR and ELISA and western blot analysis. 29096753 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 Biomarker disease BEFREE Salivary interleukin-6 in the detection of oral cancer and precancer. 25560781 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 AlteredExpression disease BEFREE Regarding clinical data, the incidence of DNMT3b immunoreactivity in oral cancer specimens was significantly higher than in non-malignant epithelium, and positively linked to expression of IL-6. 24625449 2014
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 Biomarker disease BEFREE The present study reviews the available evidence regarding the association between IL-6 and a range of oral diseases including infections (periodontal disease and endodontic infections), immunologically mediated disorders (oral lichen planus and Sjögren's syndrome) and malignancy (oral cancer and precancer). 22050374 2012
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 GeneticVariation disease BEFREE Functional variants of IL4 and IL6 genes and risk of tobacco-related oral carcinoma in high-risk Asian Indians. 21771210 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 GeneticVariation disease BEFREE Strong association of interleukin-6 -174 G>C promoter polymorphism with increased risk of oral cancer. 17177164 2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.090 Biomarker disease BEFREE Although interleukin (IL)-6 accelerates osteoclastic bone resorption, it remains unclear whether IL-6 may be involved in bone invasion of oral cancer. 11064354 2000