| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | The present study hypothesized that the use of SIgA vaccines or IL-6 inhibitors may be useful for reversing the immune deficiency associated with DCs in oral cancer. | 28454394 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | Salivary IL-8, IL-6 and TNF-α as Potential Diagnostic Biomarkers for Oral Cancer. | 28397778 | 2017 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | In this study, quantitative expression level of IL-6 and VEGF in CAF and Oral Cancer Cells (OCCs) examined through Real Time PCR and ELISA and western blot analysis. | 29096753 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | Salivary interleukin-6 in the detection of oral cancer and precancer. | 25560781 | 2015 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Regarding clinical data, the incidence of DNMT3b immunoreactivity in oral cancer specimens was significantly higher than in non-malignant epithelium, and positively linked to expression of IL-6. | 24625449 | 2014 | ||||
|
0.090 | Biomarker | disease | BEFREE | The present study reviews the available evidence regarding the association between IL-6 and a range of oral diseases including infections (periodontal disease and endodontic infections), immunologically mediated disorders (oral lichen planus and Sjögren's syndrome) and malignancy (oral cancer and precancer). | 22050374 | 2012 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Functional variants of IL4 and IL6 genes and risk of tobacco-related oral carcinoma in high-risk Asian Indians. | 21771210 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Strong association of interleukin-6 -174 G>C promoter polymorphism with increased risk of oral cancer. | 17177164 | 2007 | ||||
|
0.090 | Biomarker | disease | BEFREE | Although interleukin (IL)-6 accelerates osteoclastic bone resorption, it remains unclear whether IL-6 may be involved in bone invasion of oral cancer. | 11064354 | 2000 |