Gene: COMT ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.050 GeneticVariation phenotype BEFREE Individuals with the COMT (rs4680) Val/Val genotype (designated "warriors") withstand the onset of neuropsychiatric disorders and cognitive decline, whereas individuals with Met/Met and Val/Met genotypes ("nonwarriors") are more susceptible to these conditions. 30424994 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.050 GeneticVariation phenotype BEFREE These findings suggest that GMV compromise in the early stages of PD may be a predisposing factor for cognitive decline of COMT Val/Val homozygotes. 30612340 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.050 AlteredExpression phenotype BEFREE Our findings suggest that the high-COMT activity haplotype is associated with cognitive decline in patients with PD. 29439855 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.050 Biomarker phenotype BEFREE Besides COMT Val158/108Met polymorphism, other risk genotypes or haplotypes should be evaluated to determine the association of COMT with cognitive decline in AD. 29231139 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.050 GeneticVariation phenotype BEFREE COMT genotype predicts longitudinal cognitive decline and psychosis in 22q11.2 deletion syndrome. 16234808 2005