Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 PosttranslationalModification disease BEFREE Findings of the present study show that the epigenetic regulation of the DAT-promoter is altered in patients undergoing alcohol withdrawal. 18504048 2009
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 GeneticVariation disease BEFREE A polymorphism of the DAT gene (SLC6A3) was associated with the in vivo transporter availability and with the severity of alcohol withdrawal. 15148564 2004
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 GeneticVariation disease BEFREE Our results suggest that the A9 allele of the DAT gene is involved in vulnerability to alcohol withdrawal complications in women, but that these complications differ from those associated with this polymorphism in alcohol-dependent men. 15193761 2004
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 GeneticVariation disease BEFREE Our findings provide further evidence that the 3'UTR of the DAT1 gene affects vulnerability to severe alcohol withdrawal. 12401557 2002
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 GeneticVariation disease BEFREE In vivo availability of striatal dopamine transporter (DAT) protein has been reported to be reduced among alcoholics, and allelic variation of the DAT gene (SLC6A3) has been associated with severity of alcohol withdrawal. 10649826 2000
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 GeneticVariation disease BEFREE Based on our data, the impact of the 9-repeat allele of the dopamine transporter gene in alcoholism and the severity of alcohol withdrawal symptoms is putatively not substantial. 10088054 1999
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 GeneticVariation disease BEFREE The A9 allele of the dopamine transporter gene is associated with more severe effects of alcohol withdrawal, possibly because of modifications of the brain's capacity to compensate for long-term effects of ethanol on cerebral function. 9545991 1998
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
0.080 Biomarker disease BEFREE Our data provide evidence that a major genetic determinant of DAT1 influences vulnerability to severe alcohol withdrawal symptoms. 9024952 1997