Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | PosttranslationalModification | disease | BEFREE | Findings of the present study show that the epigenetic regulation of the DAT-promoter is altered in patients undergoing alcohol withdrawal. | 18504048 | 2009 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | A polymorphism of the DAT gene (SLC6A3) was associated with the in vivo transporter availability and with the severity of alcohol withdrawal. | 15148564 | 2004 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our results suggest that the A9 allele of the DAT gene is involved in vulnerability to alcohol withdrawal complications in women, but that these complications differ from those associated with this polymorphism in alcohol-dependent men. | 15193761 | 2004 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our findings provide further evidence that the 3'UTR of the DAT1 gene affects vulnerability to severe alcohol withdrawal. | 12401557 | 2002 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | In vivo availability of striatal dopamine transporter (DAT) protein has been reported to be reduced among alcoholics, and allelic variation of the DAT gene (SLC6A3) has been associated with severity of alcohol withdrawal. | 10649826 | 2000 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Based on our data, the impact of the 9-repeat allele of the dopamine transporter gene in alcoholism and the severity of alcohol withdrawal symptoms is putatively not substantial. | 10088054 | 1999 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The A9 allele of the dopamine transporter gene is associated with more severe effects of alcohol withdrawal, possibly because of modifications of the brain's capacity to compensate for long-term effects of ethanol on cerebral function. | 9545991 | 1998 | ||||
|
0.080 | Biomarker | disease | BEFREE | Our data provide evidence that a major genetic determinant of DAT1 influences vulnerability to severe alcohol withdrawal symptoms. | 9024952 | 1997 |