Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. 11923462 2002
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. 11923462 2002
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		0.500 Biomarker group CTD_human MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. 20711185 2010
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1 		0.500 Biomarker group CTD_human Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 19339610 2009
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists. 10900248 2000
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior. 15010698 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization. 11751029 2002
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.500 Biomarker group CTD_human A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking. 10516337 1999
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. 20494958 2010
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.500 Biomarker group CTD_human A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stress-induced reinstatement of cocaine seeking in rats. 11797056 2001
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. 15042275 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Dopamine D3 and D2 receptor mechanisms in the abuse-related behavioral effects of cocaine: studies with preferential antagonists in squirrel monkeys. 20494958 2010
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. 17332411 2007
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Effects of extended access to high versus low cocaine doses on self-administration, cocaine-induced reinstatement and brain mRNA levels in rats. 15042275 2004
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. 17332411 2007
Entrez Id: 1958
Gene Symbol: EGR1
EGR1 		0.500 Therapeutic group CTD_human Relapse to cocaine seeking increases activity-regulated gene expression differentially in the prefrontal cortex of abstinent rats. 18311559 2008
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.500 Biomarker group CTD_human Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals. 19349312 2009
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 16971900 2006
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Therapeutic group CTD_human Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. 16971900 2006
Entrez Id: 1958
Gene Symbol: EGR1
EGR1 		0.500 Therapeutic group CTD_human Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation. 16738229 2006
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.500 Biomarker group CTD_human Evidence for beta1-adrenergic receptor involvement in amygdalar corticotropin-releasing factor gene expression: implications for cocaine withdrawal. 18596687 2009
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.500 Biomarker group CTD_human Cocaine dependence and d2 receptor availability in the functional subdivisions of the striatum: relationship with cocaine-seeking behavior. 15010698 2004
Entrez Id: 1958
Gene Symbol: EGR1
EGR1 		0.500 Biomarker group CTD_human Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation. 16738229 2006