Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		0.300 Biomarker group CTD_human Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. 9888857 1999
Entrez Id: 2166
Gene Symbol: FAAH
FAAH 		0.300 Biomarker group CTD_human A missense mutation in human fatty acid amide hydrolase associated with problem drug use. 12060782 2002
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B 		0.010 GeneticVariation group LHGDN The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse. 15608559 2004
Entrez Id: 356
Gene Symbol: FASLG
FASLG 		0.200 Biomarker group RGD Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. 15644446 2005
Entrez Id: 4897
Gene Symbol: NRCAM
NRCAM 		0.300 Biomarker group CTD_human NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice. 16123759 2006
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C 		0.200 Biomarker group RGD Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. 16474401 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.200 Biomarker group RGD Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse. 16474401 2006
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.300 Biomarker group CTD_human Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward. 16901644 2006
Entrez Id: 6581
Gene Symbol: SLC22A3
SLC22A3 		0.300 Biomarker group CTD_human Association between gene polymorphisms of SLC22A3 and methamphetamine use disorder. 17010131 2006
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		0.300 Biomarker group CTD_human Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia. 17089107 2006
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.020 Biomarker group LHGDN Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia. 17217930 2007
Entrez Id: 4985
Gene Symbol: OPRD1
OPRD1 		0.300 Biomarker group CTD_human The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk. 17622222 2008
Entrez Id: 6571
Gene Symbol: SLC18A2
SLC18A2 		0.200 Biomarker group RGD A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine. 17683483 2007
Entrez Id: 1268
Gene Symbol: CNR1
CNR1 		0.300 Biomarker group CTD_human Chronic unpredictable stress enhances cocaine-conditioned place preference in type 1 cannabinoid receptor knockout mice. 18690112 2008
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker group CTD_human Neuropeptide Y augments cocaine self-administration and cocaine-induced hyperlocomotion in rats. 19063928 2009
Entrez Id: 2166
Gene Symbol: FAAH
FAAH 		0.300 Biomarker group CTD_human Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function. 19103437 2009
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4 		0.300 Biomarker group CTD_human Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression. 19272758 2009
Entrez Id: 114788
Gene Symbol: CSMD3
CSMD3 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 1962
Gene Symbol: EHHADH
EHHADH 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9271
Gene Symbol: PIWIL1
PIWIL1 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 5583
Gene Symbol: PRKCH
PRKCH 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 64131
Gene Symbol: XYLT1
XYLT1 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 55742
Gene Symbol: PARVA
PARVA 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 1826
Gene Symbol: DSCAM
DSCAM 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9128
Gene Symbol: PRPF4
PRPF4 		0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010